Mutations in Specific Structural Regions of Immunoglobulin Light Chains Are Associated with Free Light Chain Levels in Patients with AL Amyloidosis

• Tanya L. Poshusta,

  Affiliation Department of Biochemistry and Molecular Biology, College of Medicine, Mayo Clinic, Rochester, Minnesota, United States of America

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• Laura A. Sikkink,

  Affiliation Department of Biochemistry and Molecular Biology, College of Medicine, Mayo Clinic, Rochester, Minnesota, United States of America

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• Nelson Leung,

  Affiliation Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, United States of America

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• Raynell J. Clark,

  Affiliation Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America

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• Angela Dispenzieri,

  Affiliation Division of Hematology, Mayo Clinic, Rochester, Minnesota, United States of America

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• Marina Ramirez-Alvarado

  * E-mail: Ramirezalvarado.marina@mayo.edu

  Affiliation Department of Biochemistry and Molecular Biology, College of Medicine, Mayo Clinic, Rochester, Minnesota, United States of America

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