A Mathematical Model for the Detection Mechanism of DNA Double-Strand Breaks Depending on Autophosphorylation of ATM

Open Access

Peer-reviewed

Research Article

Kazunari Mouri ,

* E-mail: kmouri@kuicr.kyoto-u.ac.jp

Affiliation Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho Uji, Kyoto, Japan
⨯
Jose C. Nacher,

Affiliation Department of Complex Systems, Future University-Hakodate, Kamedanakano-cho, Hakodate, Hokkaido, Japan
⨯
Tatsuya Akutsu

Affiliation Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho Uji, Kyoto, Japan
⨯

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DNA repair
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Phosphorylation
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DNA damage
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Biochemical simulations
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Stress signaling cascade
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Algorithms
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Signal amplification
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Stochastic processes
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