Immunization with Radiation-Attenuated Plasmodium berghei Sporozoites Induces Liver cCD8α+DC that Activate CD8+T Cells against Liver-Stage Malaria

Open Access

Peer-reviewed

Research Article

Immunization with Radiation-Attenuated Plasmodium berghei Sporozoites Induces Liver cCD8α⁺DC that Activate CD8⁺T Cells against Liver-Stage Malaria

Ousman Jobe,

Affiliation Department of Cellular Immunology, Division of Malaria Vaccine Development, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America
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Gina Donofrio,

Affiliation Department of Cellular Immunology, Division of Malaria Vaccine Development, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America
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Guangping Sun,

Affiliation Department of Cellular Immunology, Division of Malaria Vaccine Development, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America
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Dmitry Liepinsh,

Affiliation Department of Cellular Immunology, Division of Malaria Vaccine Development, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America
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Robert Schwenk,

Affiliation Department of Cellular Immunology, Division of Malaria Vaccine Development, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America
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Urszula Krzych

* E-mail: urszula.krzych@.amedd.army.mil

Affiliation Department of Cellular Immunology, Division of Malaria Vaccine Development, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America
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Cytotoxic T cells
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T cells
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Sporozoites
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Spleen
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Antigen-presenting cells
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Flow cytometry
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Cell staining
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Hepatocytes
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