Paracrine Diffusion of PrP^C and Propagation of Prion Infectivity by Plasma Membrane-Derived Microvesicles

• Vincenzo Mattei ,

  Contributed equally to this work with: Vincenzo Mattei, Maria Grazia Barenco

  Affiliations Dipartimento di Medicina Sperimentale, “Sapienza” University, Rome, Italy, Laboratorio di Medicina Sperimentale e Patologia Ambientale, “Sapienza” University, Polo Universitario di Rieti “Sabina Universitas“, Rieti, Italy

  ⨯
• Maria Grazia Barenco ,

  Contributed equally to this work with: Vincenzo Mattei, Maria Grazia Barenco

  Affiliation Prion Research Group, Paul-Ehrlich-Institut, Paul-Ehrlich-Strasse, Langen, Germany

  ⨯
• Vincenzo Tasciotti,

  Affiliations Dipartimento di Medicina Sperimentale, “Sapienza” University, Rome, Italy, Laboratorio di Medicina Sperimentale e Patologia Ambientale, “Sapienza” University, Polo Universitario di Rieti “Sabina Universitas“, Rieti, Italy

  ⨯
• Tina Garofalo,

  Affiliation Dipartimento di Medicina Sperimentale, “Sapienza” University, Rome, Italy

  ⨯
• Agostina Longo,

  Affiliation Dipartimento di Medicina Sperimentale, “Sapienza” University, Rome, Italy

  ⨯
• Klaus Boller,

  Affiliation Prion Research Group, Paul-Ehrlich-Institut, Paul-Ehrlich-Strasse, Langen, Germany

  ⨯
• Johannes Löwer,

  Affiliation Prion Research Group, Paul-Ehrlich-Institut, Paul-Ehrlich-Strasse, Langen, Germany

  ⨯
• Roberta Misasi,

  Affiliation Dipartimento di Medicina Sperimentale, “Sapienza” University, Rome, Italy

  ⨯
• Fabio Montrasio,

  Affiliation Prion Research Group, Paul-Ehrlich-Institut, Paul-Ehrlich-Strasse, Langen, Germany

  ⨯
• Maurizio Sorice

  * E-mail: maurizio.sorice@uniroma1.it

  Affiliations Dipartimento di Medicina Sperimentale, “Sapienza” University, Rome, Italy, Laboratorio di Medicina Sperimentale e Patologia Ambientale, “Sapienza” University, Polo Universitario di Rieti “Sabina Universitas“, Rieti, Italy

  ⨯