The Signal Peptide of Staphylococcus aureus Panton Valentine Leukocidin LukS Component Mediates Increased Adhesion to Heparan Sulfates

Anne Tristan; Yvonne Benito; Roland Montserret; Sandrine Boisset; Eric Dusserre; Francois Penin; Florence Ruggiero; Jerome Etienne; Hugues Lortat-Jacob; Gerard Lina; M. Gabriela Bowden; François Vandenesch

doi:10.1371/journal.pone.0005042

Loading metrics

Open Access

Peer-reviewed

Research Article

The Signal Peptide of Staphylococcus aureus Panton Valentine Leukocidin LukS Component Mediates Increased Adhesion to Heparan Sulfates

Anne Tristan ,

* E-mail: anne.tristan@chu-lyon.fr

Affiliations Université Lyon 1, Faculté Laennec, Lyon, France, INSERM U851, Centre National de Référence des Staphylocoques, Lyon, France, Hospices Civils de Lyon, Centre de Biologie Est, Lyon, France
⨯
Yvonne Benito,

Affiliations INSERM U851, Centre National de Référence des Staphylocoques, Lyon, France, Hospices Civils de Lyon, Centre de Biologie Est, Lyon, France
⨯
Roland Montserret,

Affiliation Institut de Biologie et Chimie des Protéines, UMR 5086, Université de Lyon, IFR128 BioSciences Gerland-Lyon Sud, Lyon, France
⨯
Sandrine Boisset,

Affiliations Université Lyon 1, Faculté Laennec, Lyon, France, INSERM U851, Centre National de Référence des Staphylocoques, Lyon, France, Hospices Civils de Lyon, Centre de Biologie Est, Lyon, France
⨯
Eric Dusserre,

Affiliations Université Lyon 1, Faculté Laennec, Lyon, France, INSERM U851, Centre National de Référence des Staphylocoques, Lyon, France
⨯
Francois Penin,

Affiliation Institut de Biologie et Chimie des Protéines, UMR 5086, Université de Lyon, IFR128 BioSciences Gerland-Lyon Sud, Lyon, France
⨯
Florence Ruggiero,

Affiliation Institut de Biologie et Chimie des Protéines, UMR 5086, Université de Lyon, IFR128 BioSciences Gerland-Lyon Sud, Lyon, France
⨯
Jerome Etienne,

Affiliations Université Lyon 1, Faculté Laennec, Lyon, France, INSERM U851, Centre National de Référence des Staphylocoques, Lyon, France, Hospices Civils de Lyon, Centre de Biologie Est, Lyon, France
⨯
Hugues Lortat-Jacob,

Affiliation Institut de Biologie Structurale, UMR 5075 CEA-CNRS-UJF, Grenoble, France
⨯
Gerard Lina,

Affiliations Université Lyon 1, Faculté Laennec, Lyon, France, INSERM U851, Centre National de Référence des Staphylocoques, Lyon, France, Hospices Civils de Lyon, Centre de Biologie Est, Lyon, France
⨯
M. Gabriela Bowden,

Affiliation Center for Extracellular Matrix Biology, Institute of Biosciences and Technology, The Texas A&M University System Health Science Center, Houston, Texas, United States of America
⨯
François Vandenesch

Affiliations Université Lyon 1, Faculté Laennec, Lyon, France, INSERM U851, Centre National de Référence des Staphylocoques, Lyon, France, Hospices Civils de Lyon, Centre de Biologie Est, Lyon, France
⨯

The Signal Peptide of Staphylococcus aureus Panton Valentine Leukocidin LukS Component Mediates Increased Adhesion to Heparan Sulfates

Anne Tristan,
Yvonne Benito,
Roland Montserret,
Sandrine Boisset,
Eric Dusserre,
Francois Penin,
Florence Ruggiero,
Jerome Etienne,
Hugues Lortat-Jacob,
Gerard Lina

Published: April 6, 2009
https://doi.org/10.1371/journal.pone.0005042

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Signal peptides
Is the Subject Area "Signal peptides" applicable to this article?

Thanks for your feedback.
Collagens
Is the Subject Area "Collagens" applicable to this article?

Thanks for your feedback.
Sulfates
Is the Subject Area "Sulfates" applicable to this article?

Thanks for your feedback.
Staphylococcus aureus
Is the Subject Area "Staphylococcus aureus" applicable to this article?

Thanks for your feedback.
Extracellular matrix
Is the Subject Area "Extracellular matrix" applicable to this article?

Thanks for your feedback.
Extracellular matrix proteins
Is the Subject Area "Extracellular matrix proteins" applicable to this article?

Thanks for your feedback.
Plasmid construction
Is the Subject Area "Plasmid construction" applicable to this article?

Thanks for your feedback.
Lactococcus lactis
Is the Subject Area "Lactococcus lactis" applicable to this article?

Thanks for your feedback.