Development of Epitope-Blocking ELISA for Universal Detection of Antibodies to Human H5N1 Influenza Viruses

Mookkan Prabakaran; Hui-Ting Ho; Nayana Prabhu; Sumathy Velumani; Milene Szyporta; Fang He; Kwai-Peng Chan; Li-Mei Chen; Yumiko Matsuoka; Ruben O. Donis; Jimmy Kwang

doi:10.1371/journal.pone.0004566

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Open Access

Peer-reviewed

Research Article

Development of Epitope-Blocking ELISA for Universal Detection of Antibodies to Human H5N1 Influenza Viruses

Mookkan Prabakaran,

Affiliation Animal Health Biotechnology, Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Singapore
⨯
Hui-Ting Ho,

Affiliation Animal Health Biotechnology, Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Singapore
⨯
Nayana Prabhu,

Affiliation Animal Health Biotechnology, Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Singapore
⨯
Sumathy Velumani,

Affiliation Animal Health Biotechnology, Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Singapore
⨯
Milene Szyporta,

Affiliation Animal Health Biotechnology, Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Singapore
⨯
Fang He,

Affiliation Animal Health Biotechnology, Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Singapore
⨯
Kwai-Peng Chan,

Affiliation Department of Pathology, Singapore General Hospital, Singapore, Singapore
⨯
Li-Mei Chen,

Affiliation Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Yumiko Matsuoka,

Affiliation Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Ruben O. Donis,

Affiliation Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Jimmy Kwang

* E-mail: kwang@tll.org.sg

Affiliations Animal Health Biotechnology, Temasek Life Sciences Laboratory, National University of Singapore, Singapore, Singapore, Department of Microbiology, Faculty of Medicine, National University of Singapore, Singapore, Singapore
⨯

Development of Epitope-Blocking ELISA for Universal Detection of Antibodies to Human H5N1 Influenza Viruses

Mookkan Prabakaran,
Hui-Ting Ho,
Nayana Prabhu,
Sumathy Velumani,
Milene Szyporta,
Fang He,
Kwai-Peng Chan,
Li-Mei Chen,
Yumiko Matsuoka,
Ruben O. Donis

Published: February 24, 2009
https://doi.org/10.1371/journal.pone.0004566

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