Heterozygous Mutation of Opa1 in Drosophila Shortens Lifespan Mediated through Increased Reactive Oxygen Species Production

• Sha Tang,

  Affiliation Division of Human Genetics, Department of Pediatrics, University of California Irvine, Irvine, California, United States of America

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• Phung Khanh Le,

  Affiliation Division of Human Genetics, Department of Pediatrics, University of California Irvine, Irvine, California, United States of America

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• Stephanie Tse,

  Affiliation Division of Human Genetics, Department of Pediatrics, University of California Irvine, Irvine, California, United States of America

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• Douglas C. Wallace,

  Affiliations Center for Molecular and Mitochondrial Medicine and Genetics, University of California Irvine, Irvine, California, United States of America, Department of Biological Chemistry, University of California Irvine, Irvine, California, United States of America

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• Taosheng Huang

  * E-mail: huangts@uci.edu

  Affiliations Division of Human Genetics, Department of Pediatrics, University of California Irvine, Irvine, California, United States of America, Center for Molecular and Mitochondrial Medicine and Genetics, University of California Irvine, Irvine, California, United States of America, Department of Developmental and Cell Biology, University of California Irvine, Irvine, California, United States of America, Department of Pathology, University of California Irvine, Irvine, California, United States of America

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