Impaired Nuclear Nrf2 Translocation Undermines the Oxidative Stress Response in Friedreich Ataxia

Vincent Paupe; Emmanuel P. Dassa; Sergio Goncalves; Françoise Auchère; Maria Lönn; Arne Holmgren; Pierre Rustin

doi:10.1371/journal.pone.0004253

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Research Article

Impaired Nuclear Nrf2 Translocation Undermines the Oxidative Stress Response in Friedreich Ataxia

Vincent Paupe,

Affiliations Inserm, U676, Hôpital Robert Debré, Bât. Ecran, Paris, France, Faculté de médecine Denis Diderot, IFR02, Université Paris 7, Laboratoire d'Ingénierie des Protéines et Contrôle Métabolique, Paris, France
⨯
Emmanuel P. Dassa,

Affiliations Inserm, U676, Hôpital Robert Debré, Bât. Ecran, Paris, France, Faculté de médecine Denis Diderot, IFR02, Université Paris 7, Laboratoire d'Ingénierie des Protéines et Contrôle Métabolique, Paris, France
⨯
Sergio Goncalves,

Affiliations Inserm, U676, Hôpital Robert Debré, Bât. Ecran, Paris, France, Faculté de médecine Denis Diderot, IFR02, Université Paris 7, Laboratoire d'Ingénierie des Protéines et Contrôle Métabolique, Paris, France
⨯
Françoise Auchère,

Affiliation Département de Biologie des Génomes, Institut Jacques Monod (UMR 7592 CNRS - Universités Paris 6 & 7), Paris, France
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Maria Lönn,

Affiliation Medical Nobel Institute for Biochemistry, Department of Medical Biochemistry and Biophysics Karolinska Institutet, Stockholm, Sweden
⨯
Arne Holmgren,

Affiliation Medical Nobel Institute for Biochemistry, Department of Medical Biochemistry and Biophysics Karolinska Institutet, Stockholm, Sweden
⨯
Pierre Rustin

* E-mail: pierre.rustin@inserm.fr

Affiliations Inserm, U676, Hôpital Robert Debré, Bât. Ecran, Paris, France, Faculté de médecine Denis Diderot, IFR02, Université Paris 7, Laboratoire d'Ingénierie des Protéines et Contrôle Métabolique, Paris, France
⨯

Impaired Nuclear Nrf2 Translocation Undermines the Oxidative Stress Response in Friedreich Ataxia

Vincent Paupe,
Emmanuel P. Dassa,
Sergio Goncalves,
Françoise Auchère,
Maria Lönn,
Arne Holmgren,
Pierre Rustin

Published: January 22, 2009
https://doi.org/10.1371/journal.pone.0004253

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