Host HLA B*Allele-Associated Multi-Clade Gag T-Cell Recognition Correlates with Slow HIV-1 Disease Progression in Antiretroviral Therapy-Naïve Ugandans

Jennifer Serwanga; Leigh Anne Shafer; Edward Pimego; Betty Auma; Christine Watera; Samantha Rowland; David Yirrell; Pietro Pala; Heiner Grosskurth; Jimmy Whitworth; Frances Gotch; Pontiano Kaleebu

doi:10.1371/journal.pone.0004188

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Open Access

Peer-reviewed

Research Article

Host HLA B*Allele-Associated Multi-Clade Gag T-Cell Recognition Correlates with Slow HIV-1 Disease Progression in Antiretroviral Therapy-Naïve Ugandans

Jennifer Serwanga ,

* E-mail: jennifer.serwanga@mrcuganda.org

Affiliation MRC/UVRI Uganda Research Unit on AIDS, c/o Uganda Virus Research Institute, Entebbe, Uganda
⨯
Leigh Anne Shafer,

Affiliation MRC/UVRI Uganda Research Unit on AIDS, c/o Uganda Virus Research Institute, Entebbe, Uganda
⨯
Edward Pimego,

Affiliation MRC/UVRI Uganda Research Unit on AIDS, c/o Uganda Virus Research Institute, Entebbe, Uganda
⨯
Betty Auma,

Affiliation MRC/UVRI Uganda Research Unit on AIDS, c/o Uganda Virus Research Institute, Entebbe, Uganda
⨯
Christine Watera,

Affiliation MRC/UVRI Uganda Research Unit on AIDS, c/o Uganda Virus Research Institute, Entebbe, Uganda
⨯
Samantha Rowland,

Affiliation Department of Immunology, Imperial College, Chelsea & Westminster Hospital, London, United Kingdom
⨯
David Yirrell,

Affiliation Department of Medical Microbiology, Ninewells Hospital, Dundee, United Kingdom
⨯
Pietro Pala,

Affiliation MRC/UVRI Uganda Research Unit on AIDS, c/o Uganda Virus Research Institute, Entebbe, Uganda
⨯
Heiner Grosskurth,

Affiliation MRC/UVRI Uganda Research Unit on AIDS, c/o Uganda Virus Research Institute, Entebbe, Uganda
⨯
Jimmy Whitworth,

Affiliation MRC/UVRI Uganda Research Unit on AIDS, c/o Uganda Virus Research Institute, Entebbe, Uganda
⨯
Frances Gotch,

Affiliation Department of Immunology, Imperial College, Chelsea & Westminster Hospital, London, United Kingdom
⨯
Pontiano Kaleebu

Affiliation MRC/UVRI Uganda Research Unit on AIDS, c/o Uganda Virus Research Institute, Entebbe, Uganda
⨯

Host HLA B*Allele-Associated Multi-Clade Gag T-Cell Recognition Correlates with Slow HIV-1 Disease Progression in Antiretroviral Therapy-Naïve Ugandans

Jennifer Serwanga,
Leigh Anne Shafer,
Edward Pimego,
Betty Auma,
Christine Watera,
Samantha Rowland,
David Yirrell,
Pietro Pala,
Heiner Grosskurth,
Jimmy Whitworth

Published: January 14, 2009
https://doi.org/10.1371/journal.pone.0004188

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