Akt Regulates Drug-Induced Cell Death through Bcl-w Downregulation

Michela Garofalo; Cristina Quintavalle; Ciro Zanca; Assunta De Rienzo; Giulia Romano; Mario Acunzo; Loredana Puca; Mariarosaria Incoronato; Carlo M. Croce; Gerolama Condorelli

doi:10.1371/journal.pone.0004070

Loading metrics

Open Access

Peer-reviewed

Research Article

Akt Regulates Drug-Induced Cell Death through Bcl-w Downregulation

Michela Garofalo ,

Contributed equally to this work with: Michela Garofalo, Cristina Quintavalle

Affiliations Department of Cellular and Molecular Biology and Pathology, “Federico II” University of Naples, Naples, Italy, Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America
⨯
Cristina Quintavalle ,

Contributed equally to this work with: Michela Garofalo, Cristina Quintavalle

Affiliations Department of Cellular and Molecular Biology and Pathology, “Federico II” University of Naples, Naples, Italy, IEOS, CNR, Naples, Italy
⨯
Ciro Zanca,

Affiliation Department of Cellular and Molecular Biology and Pathology, “Federico II” University of Naples, Naples, Italy
⨯
Assunta De Rienzo,

Affiliation IRGS, Biogem s.c.ar.l., Ariano Irpino (AV), Italy
⨯
Giulia Romano,

Affiliation Fondazione SDN, Naples, Italy
⨯
Mario Acunzo,

Affiliations Department of Cellular and Molecular Biology and Pathology, “Federico II” University of Naples, Naples, Italy, IEOS, CNR, Naples, Italy
⨯
Loredana Puca,

Affiliation Department of Cellular and Molecular Biology and Pathology, “Federico II” University of Naples, Naples, Italy
⨯
Mariarosaria Incoronato,

Affiliation Fondazione SDN, Naples, Italy
⨯
Carlo M. Croce,

Affiliation Department of Molecular Virology, Immunology and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America
⨯
Gerolama Condorelli

* E-mail: gecondor@unina.it

Affiliations Department of Cellular and Molecular Biology and Pathology, “Federico II” University of Naples, Naples, Italy, IEOS, CNR, Naples, Italy, Facoltà di Scienze Biotecnologiche, “Federico II” University of Naples, Naples, Italy
⨯

Akt Regulates Drug-Induced Cell Death through Bcl-w Downregulation

Michela Garofalo,
Cristina Quintavalle,
Ciro Zanca,
Assunta De Rienzo,
Giulia Romano,
Mario Acunzo,
Loredana Puca,
Mariarosaria Incoronato,
Carlo M. Croce,
Gerolama Condorelli

Published: December 30, 2008
https://doi.org/10.1371/journal.pone.0004070

Reader Comments (1)

Post a new comment on this article

0 Responses

07 Feb 2020
23:44 GMT
Most Recent

Notification from the PLOS ONE Editors Posted by PLOS_ONE_Group on 07 Feb 2020 at 23:44 GMT

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Immunoprecipitation
Is the Subject Area "Immunoprecipitation" applicable to this article?

Thanks for your feedback.
Apoptosis
Is the Subject Area "Apoptosis" applicable to this article?

Thanks for your feedback.
Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
HeLa cells
Is the Subject Area "HeLa cells" applicable to this article?

Thanks for your feedback.
Protein extraction
Is the Subject Area "Protein extraction" applicable to this article?

Thanks for your feedback.
Co-immunoprecipitation
Is the Subject Area "Co-immunoprecipitation" applicable to this article?

Thanks for your feedback.
Drug interactions
Is the Subject Area "Drug interactions" applicable to this article?

Thanks for your feedback.
Mitochondria
Is the Subject Area "Mitochondria" applicable to this article?

Thanks for your feedback.