Olig2-Induced Neural Stem Cell Differentiation Involves Downregulation of Wnt Signaling and Induction of Dickkopf-1 Expression

Sung-Min Ahn; Kyunghee Byun; Deokhoon Kim; Kiyoung Lee; Jong Shin Yoo; Seung U. Kim; Eek-hoon Jho; Richard J. Simpson; Bonghee Lee

doi:10.1371/journal.pone.0003917

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Peer-reviewed

Research Article

Olig2-Induced Neural Stem Cell Differentiation Involves Downregulation of Wnt Signaling and Induction of Dickkopf-1 Expression

Sung-Min Ahn ,

Contributed equally to this work with: Sung-Min Ahn, Kyunghee Byun

Affiliation Center for Genomics and Proteomics, Lee Gil Ya Cancer and Diabetes Institute, Gachon University of Medicine and Science, Incheon, Korea
⨯
Kyunghee Byun ,

Contributed equally to this work with: Sung-Min Ahn, Kyunghee Byun

Affiliation Center for Genomics and Proteomics, Lee Gil Ya Cancer and Diabetes Institute, Gachon University of Medicine and Science, Incheon, Korea
⨯
Deokhoon Kim,

Affiliation Center for Genomics and Proteomics, Lee Gil Ya Cancer and Diabetes Institute, Gachon University of Medicine and Science, Incheon, Korea
⨯
Kiyoung Lee,

Affiliation Center for Genomics and Proteomics, Lee Gil Ya Cancer and Diabetes Institute, Gachon University of Medicine and Science, Incheon, Korea
⨯
Jong Shin Yoo,

Affiliation Mass Spectrometry Analysis Group, Korea Basic Science Institute, Daejeon, Korea
⨯
Seung U. Kim ,

* E-mail: sukim2005@gmail.com (SUK); Richard.simpson@ludwig.edu.au (RJS); bhlee@gachon.ac.kr (BL)

Affiliations Gachon Institute for Regenerative Medicine, Gachon University of Medicine and Science, Incheon, Korea, Department of Medicine, University of British Columbia, Vancouver, Canada
⨯
Eek-hoon Jho,

Affiliation Department of Life Science, The University of Seoul, Dongdaemun-gu, Seoul, Korea
⨯
Richard J. Simpson ,

* E-mail: sukim2005@gmail.com (SUK); Richard.simpson@ludwig.edu.au (RJS); bhlee@gachon.ac.kr (BL)

Affiliation Joint Proteomics Laboratory, Ludwig Institute for Cancer Research & the Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia
⨯
Bonghee Lee

* E-mail: sukim2005@gmail.com (SUK); Richard.simpson@ludwig.edu.au (RJS); bhlee@gachon.ac.kr (BL)

Affiliation Center for Genomics and Proteomics, Lee Gil Ya Cancer and Diabetes Institute, Gachon University of Medicine and Science, Incheon, Korea
⨯

Olig2-Induced Neural Stem Cell Differentiation Involves Downregulation of Wnt Signaling and Induction of Dickkopf-1 Expression

Sung-Min Ahn,
Kyunghee Byun,
Deokhoon Kim,
Kiyoung Lee,
Jong Shin Yoo,
Seung U. Kim,
Eek-hoon Jho,
Richard J. Simpson,
Bonghee Lee

Published: December 18, 2008
https://doi.org/10.1371/journal.pone.0003917

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