c-Myc Is Required for Maintenance of Glioma Cancer Stem Cells

Jialiang Wang; Hui Wang; Zhizhong Li; Qiulian Wu; Justin D. Lathia; Roger E. McLendon; Anita B. Hjelmeland; Jeremy N. Rich

doi:10.1371/journal.pone.0003769

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Open Access

Peer-reviewed

Research Article

c-Myc Is Required for Maintenance of Glioma Cancer Stem Cells

Jialiang Wang,

Affiliations Department of Surgery, Duke University, Durham, North Carolina, United States of America, Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Hui Wang,

Affiliations Department of Pharmacology and Cancer Biology, Duke University, Durham, North Carolina, United States of America, Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Zhizhong Li,

Affiliations Department of Pharmacology and Cancer Biology, Duke University, Durham, North Carolina, United States of America, Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Qiulian Wu,

Affiliations Department of Surgery, Duke University, Durham, North Carolina, United States of America, Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Justin D. Lathia,

Affiliations Department of Surgery, Duke University, Durham, North Carolina, United States of America, Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Roger E. McLendon,

Affiliations Department of Pathology, Duke University, Durham, North Carolina, United States of America, Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Anita B. Hjelmeland,

Affiliations Department of Surgery, Duke University, Durham, North Carolina, United States of America, Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Jeremy N. Rich

* E-mail: richj@ccf.org

Affiliations Department of Surgery, Duke University, Durham, North Carolina, United States of America, Department of Pharmacology and Cancer Biology, Duke University, Durham, North Carolina, United States of America, Department of Medicine, Duke University, Durham, North Carolina, United States of America, Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Stem Cell Biology and Regenerative Biology, Cleveland Clinic, Cleveland, Ohio, United States of America
⨯

c-Myc Is Required for Maintenance of Glioma Cancer Stem Cells

Jialiang Wang,
Hui Wang,
Zhizhong Li,
Qiulian Wu,
Justin D. Lathia,
Roger E. McLendon,
Anita B. Hjelmeland,
Jeremy N. Rich

Published: November 20, 2008
https://doi.org/10.1371/journal.pone.0003769

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