Anti-EGFR Antibody Efficiently and Specifically Inhibits Human TSC2−/− Smooth Muscle Cell Proliferation. Possible Treatment Options for TSC and LAM

Open Access

Peer-reviewed

Research Article

Anti-EGFR Antibody Efficiently and Specifically Inhibits Human TSC2⁻/⁻ Smooth Muscle Cell Proliferation. Possible Treatment Options for TSC and LAM

Elena Lesma ,

* E-mail: elena.lesma@unimi.it

Affiliation Laboratory of Pharmacology , Department of Medicine, Surgery and Dentistry- Polo H. San Paolo, Faculty of Medicine, University of Milan, Milan, Italy
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Vera Grande,

Affiliation Laboratory of Pharmacology , Department of Medicine, Surgery and Dentistry- Polo H. San Paolo, Faculty of Medicine, University of Milan, Milan, Italy
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Silvia Ancona,

Affiliation Laboratory of Pharmacology , Department of Medicine, Surgery and Dentistry- Polo H. San Paolo, Faculty of Medicine, University of Milan, Milan, Italy
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Stephana Carelli,

Affiliation Laboratory of Pharmacology , Department of Medicine, Surgery and Dentistry- Polo H. San Paolo, Faculty of Medicine, University of Milan, Milan, Italy
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Anna Maria Di Giulio,

Affiliation Laboratory of Pharmacology , Department of Medicine, Surgery and Dentistry- Polo H. San Paolo, Faculty of Medicine, University of Milan, Milan, Italy
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Alfredo Gorio

Affiliations Laboratory of Pharmacology , Department of Medicine, Surgery and Dentistry- Polo H. San Paolo, Faculty of Medicine, University of Milan, Milan, Italy, Clinical Pharmacology, IRCCS Humanitas, Milan, Italy
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Transfection
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Small interfering RNA
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Cell signaling
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Phosphorylation
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Cell growth
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Cell proliferation
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Smooth muscle cells
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Head and neck cancers
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