The Specificity and Polymorphism of the MHC Class I Prevents the Global Adaptation of HIV-1 to the Monomorphic Proteasome and TAP

Open Access

Peer-reviewed

Research Article

Boris Schmid V ,

* E-mail: boris.schmid@gmail.com

Affiliation Institute of Theoretical Biology, Utrecht University, Utrecht, the Netherlands
⨯
Can Keşmir,

Affiliations Institute of Theoretical Biology, Utrecht University, Utrecht, the Netherlands, Academic Biomedical Centre, Utrecht University, Utrecht, the Netherlands
⨯
Rob J. de Boer

Affiliation Institute of Theoretical Biology, Utrecht University, Utrecht, the Netherlands
⨯

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Antigen presentation
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HIV-1
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Major histocompatibility complex
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Proteasomes
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Antigen processing and recognition
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T cells
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Cytotoxic T cells
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Evolutionary adaptation
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