Wnt5a Regulates Ventral Midbrain Morphogenesis and the Development of A9–A10 Dopaminergic Cells In Vivo

Emma R. Andersson; Nilima Prakash; Lukas Cajanek; Eleonora Minina; Vitezslav Bryja; Lenka Bryjova; Terry P. Yamaguchi; Anita C. Hall; Wolfgang Wurst; Ernest Arenas

doi:10.1371/journal.pone.0003517

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Peer-reviewed

Research Article

Wnt5a Regulates Ventral Midbrain Morphogenesis and the Development of A9–A10 Dopaminergic Cells In Vivo

Emma R. Andersson,

Affiliation Laboratory of Molecular Neurobiology, Department of Medical Biochemistry & Biophysics, Karolinska Institutet, Stockholm, Sweden
⨯
Nilima Prakash,

Affiliation Helmholtz Centre Munich, German Research Centre for Environmental Health, and Technical University Munich, Institute of Developmental Genetics, Munich/Neuherberg, Germany
⨯
Lukas Cajanek ,

Contributed equally to this work with: Lukas Cajanek, Eleonora Minina, Wolfgang Wurst, Ernest Arenas

Affiliation Laboratory of Molecular Neurobiology, Department of Medical Biochemistry & Biophysics, Karolinska Institutet, Stockholm, Sweden
⨯
Eleonora Minina ,

Contributed equally to this work with: Lukas Cajanek, Eleonora Minina, Wolfgang Wurst, Ernest Arenas

Affiliation Helmholtz Centre Munich, German Research Centre for Environmental Health, and Technical University Munich, Institute of Developmental Genetics, Munich/Neuherberg, Germany
⨯
Vitezslav Bryja,

Affiliations Laboratory of Molecular Neurobiology, Department of Medical Biochemistry & Biophysics, Karolinska Institutet, Stockholm, Sweden, Department of Cytokinetics, Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno, Czech Republic, Institute of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic
⨯
Lenka Bryjova,

Affiliations Laboratory of Molecular Neurobiology, Department of Medical Biochemistry & Biophysics, Karolinska Institutet, Stockholm, Sweden, Department of Cytokinetics, Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno, Czech Republic, Institute of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic
⨯
Terry P. Yamaguchi,

Affiliation Cancer and Developmental Biology Laboratory, National Cancer Institute-Frederick, Frederick, Maryland, United States of America
⨯
Anita C. Hall,

Affiliation Division of Cell and Molecular Biology, Imperial College London, London, United Kingdom
⨯
Wolfgang Wurst ,

Contributed equally to this work with: Lukas Cajanek, Eleonora Minina, Wolfgang Wurst, Ernest Arenas

* E-mail: wurst@helmholtz-muenchen.de (WW); ernest.arenas@ki.se (EA)

Affiliations Helmholtz Centre Munich, German Research Centre for Environmental Health, and Technical University Munich, Institute of Developmental Genetics, Munich/Neuherberg, Germany, Max-Planck-Institute of Psychiatry, Munich, Germany
⨯
Ernest Arenas

Contributed equally to this work with: Lukas Cajanek, Eleonora Minina, Wolfgang Wurst, Ernest Arenas

* E-mail: wurst@helmholtz-muenchen.de (WW); ernest.arenas@ki.se (EA)

Affiliation Laboratory of Molecular Neurobiology, Department of Medical Biochemistry & Biophysics, Karolinska Institutet, Stockholm, Sweden
⨯

Wnt5a Regulates Ventral Midbrain Morphogenesis and the Development of A9–A10 Dopaminergic Cells In Vivo

Emma R. Andersson,
Nilima Prakash,
Lukas Cajanek,
Eleonora Minina,
Vitezslav Bryja,
Lenka Bryjova,
Terry P. Yamaguchi,
Anita C. Hall,
Wolfgang Wurst,
Ernest Arenas

Published: October 27, 2008
https://doi.org/10.1371/journal.pone.0003517

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Midbrain
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Neuronal differentiation
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Neurons
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Wnt signaling cascade
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