Dysfunction of Nrf-2 in CF Epithelia Leads to Excess Intracellular H2O2 and Inflammatory Cytokine Production

Open Access

Peer-reviewed

Research Article

Dysfunction of Nrf-2 in CF Epithelia Leads to Excess Intracellular H₂O₂ and Inflammatory Cytokine Production

Junnan Chen,

Affiliation Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯
Michael Kinter,

Affiliation Free Radical Biology and Aging Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America
⨯
Samuel Shank,

Affiliation Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯
Calvin Cotton,

Affiliation Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯
Thomas J. Kelley,

Affiliation Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯
Assem G. Ziady

* E-mail: agz2@case.edu

Affiliation Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯

Cytokines
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Inflammation
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Cystic fibrosis
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Transfection
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Antioxidants
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Cytokine therapy
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Luciferase
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Oxidation-reduction reactions
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