Signal Regulatory Protein α Negatively Regulates β2 Integrin-Mediated Monocyte Adhesion, Transendothelial Migration and Phagocytosis

Dan-Qing Liu; Li-Min Li; Ya-Lan Guo; Rui Bai; Chen Wang; Zhen Bian; Chen-Yu Zhang; Ke Zen

doi:10.1371/journal.pone.0003291

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Peer-reviewed

Research Article

Signal Regulatory Protein α Negatively Regulates β₂ Integrin-Mediated Monocyte Adhesion, Transendothelial Migration and Phagocytosis

Dan-Qing Liu,

Affiliation Jiangsu Diabetes Research Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China
⨯
Li-Min Li,

Affiliations Jiangsu Diabetes Research Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China, Jiangsu CDC-Nanjing University Joint Institute for Virology, Nanjing, Jiangsu, China
⨯
Ya-Lan Guo,

Affiliation Jiangsu Diabetes Research Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China
⨯
Rui Bai,

Affiliation Jiangsu Diabetes Research Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China
⨯
Chen Wang,

Affiliation Jiangsu Diabetes Research Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China
⨯
Zhen Bian,

Affiliation Jiangsu Diabetes Research Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China
⨯
Chen-Yu Zhang,

Affiliation Jiangsu Diabetes Research Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China
⨯
Ke Zen

* E-mail: kzen@nju.edu.cn

Affiliations Jiangsu Diabetes Research Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China, Jiangsu CDC-Nanjing University Joint Institute for Virology, Nanjing, Jiangsu, China
⨯

Signal Regulatory Protein α Negatively Regulates β₂ Integrin-Mediated Monocyte Adhesion, Transendothelial Migration and Phagocytosis

Dan-Qing Liu,
Li-Min Li,
Ya-Lan Guo,
Rui Bai,
Chen Wang,
Zhen Bian,
Chen-Yu Zhang,
Ke Zen

Published: September 29, 2008
https://doi.org/10.1371/journal.pone.0003291

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Monocytes
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Integrins
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Inflammation
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Actin polymerization
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White blood cells
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Cell adhesion
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Flow cytometry
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