iTRAQ Analysis of Complex Proteome Alterations in 3xTgAD Alzheimer's Mice: Understanding the Interface between Physiology and Disease

Open Access

Peer-reviewed

Research Article

Bronwen Martin,

Affiliation Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, Biomedical Research Center, Baltimore, Maryland, United States of America
⨯
Randall Brenneman,

Affiliation Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, Biomedical Research Center, Baltimore, Maryland, United States of America
⨯
Kevin G. Becker,

Affiliation Research Resources Branch, National Institute on Aging Intramural Research Program, Biomedical Research Center, Baltimore, Maryland, United States of America
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Marjan Gucek,

Affiliation Mass Spectrometry/Proteomics Facility at Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America
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Robert N. Cole,

Affiliation Mass Spectrometry/Proteomics Facility at Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America
⨯
Stuart Maudsley

* E-mail: maudsleyst@grc.nia.nih.gov

Affiliation Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, Biomedical Research Center, Baltimore, Maryland, United States of America
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Hippocampus
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DNA-binding proteins
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Alzheimer's disease
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Mouse models
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Protein kinase C signaling
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Mitochondria
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Precursor cells
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DNA libraries
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