A Triad of Lys12, Lys41, Arg78 Spatial Domain, a Novel Identified Heparin Binding Site on Tat Protein, Facilitates Tat-Driven Cell Adhesion

Jing Ai; Xianliang Xin; Mingyue Zheng; Shuai Wang; Shuying Peng; Jing Li; Limei Wang; Hualiang Jiang; Meiyu Geng

doi:10.1371/journal.pone.0002662

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Peer-reviewed

Research Article

A Triad of Lys12, Lys41, Arg78 Spatial Domain, a Novel Identified Heparin Binding Site on Tat Protein, Facilitates Tat-Driven Cell Adhesion

Jing Ai ,

Contributed equally to this work with: Jing Ai, Xianliang Xin

Affiliation Department of Pharmacology and Glycobiology, Marine Drug and Food Institute, Ocean University of China, Qingdao, People's Republic of China
⨯
Xianliang Xin ,

Contributed equally to this work with: Jing Ai, Xianliang Xin

Affiliation Department of Pharmacology and Glycobiology, Marine Drug and Food Institute, Ocean University of China, Qingdao, People's Republic of China
⨯
Mingyue Zheng,

Affiliation Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, People's Republic of China
⨯
Shuai Wang,

Affiliation Division of Anti-tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, People's Republic of China
⨯
Shuying Peng,

Affiliation Laboratory of Mass Spectrometry, Departmant of Analytical Chemistry, Shanghai Institute of Materia Medica,Chinese Academy of Sciences, Shanghai, People's Republic of China
⨯
Jing Li,

Affiliation Department of Pharmacology and Glycobiology, Marine Drug and Food Institute, Ocean University of China, Qingdao, People's Republic of China
⨯
Limei Wang,

Affiliation Department of Pharmacology and Glycobiology, Marine Drug and Food Institute, Ocean University of China, Qingdao, People's Republic of China
⨯
Hualiang Jiang ,

* E-mail: gengmy@ouc.edu.cn (MG); hljiang@mail.shcnc.ac.cn (HJ)

Affiliation Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, People's Republic of China
⨯
Meiyu Geng

* E-mail: gengmy@ouc.edu.cn (MG); hljiang@mail.shcnc.ac.cn (HJ)

Affiliations Department of Pharmacology and Glycobiology, Marine Drug and Food Institute, Ocean University of China, Qingdao, People's Republic of China, Division of Anti-tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, People's Republic of China
⨯

A Triad of Lys12, Lys41, Arg78 Spatial Domain, a Novel Identified Heparin Binding Site on Tat Protein, Facilitates Tat-Driven Cell Adhesion

Jing Ai,
Xianliang Xin,
Mingyue Zheng,
Shuai Wang,
Shuying Peng,
Jing Li,
Limei Wang,
Hualiang Jiang,
Meiyu Geng

Published: July 16, 2008
https://doi.org/10.1371/journal.pone.0002662

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