Periodontal Tissue Regeneration Using Fibroblast Growth Factor -2: Randomized Controlled Phase II Clinical Trial

Masahiro Kitamura; Keisuke Nakashima; Yusuke Kowashi; Takeo Fujii; Hidetoshi Shimauchi; Takashi Sasano; Toshi Furuuchi; Mitsuo Fukuda; Toshihide Noguchi; Toshiaki Shibutani; Yukio Iwayama; Shogo Takashiba; Hidemi Kurihara; Masami Ninomiya; Jun-ichi Kido; Toshihiko Nagata; Takafumi Hamachi; Katsumasa Maeda; Yoshitaka Hara; Yuichi Izumi; Takao Hirofuji; Enyu Imai; Masatoshi Omae; Mitsuru Watanuki; Shinya Murakami

doi:10.1371/journal.pone.0002611

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Peer-reviewed

Research Article

Periodontal Tissue Regeneration Using Fibroblast Growth Factor -2: Randomized Controlled Phase II Clinical Trial

Masahiro Kitamura,

Affiliation Osaka University Dental Hospital, Suita, Japan
⨯
Keisuke Nakashima,

Affiliation Dental Hospital, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan
⨯
Yusuke Kowashi,

Affiliation Dental Hospital, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan
⨯
Takeo Fujii,

Affiliation Medical and Dental Clinic, Health Sciences University of Hokkaido, Sapporo, Japan
⨯
Hidetoshi Shimauchi,

Affiliation Tohoku University Dental Hospital, Sendai, Japan
⨯
Takashi Sasano,

Affiliation Tohoku University Dental Hospital, Sendai, Japan
⨯
Toshi Furuuchi,

Affiliation Tohoku University Dental Hospital, Sendai, Japan
⨯
Mitsuo Fukuda,

Affiliation Aichigakuin University Dental Hospital, Nagoya, Japan
⨯
Toshihide Noguchi,

Affiliation Aichigakuin University Dental Hospital, Nagoya, Japan
⨯
Toshiaki Shibutani,

Affiliation Asahi University Dental Hospital, Mizuho, Japan
⨯
Yukio Iwayama,

Affiliation Asahi University Dental Hospital, Mizuho, Japan
⨯
Shogo Takashiba,

Affiliation Okayama University Hospital of Dentistry, Okayama, Japan
⨯
Hidemi Kurihara,

Affiliation Hiroshima University Hospital of Dentistry, Hiroshima, Japan
⨯
Masami Ninomiya,

Affiliation Tokushima University Dental Hospital, Tokushima, Japan
⨯
Jun-ichi Kido,

Affiliation Tokushima University Dental Hospital, Tokushima, Japan
⨯
Toshihiko Nagata,

Affiliation Tokushima University Dental Hospital, Tokushima, Japan
⨯
Takafumi Hamachi,

Affiliation Kyushu University Dental Hospital, Fukuoka, Japan
⨯
Katsumasa Maeda,

Affiliation Kyushu University Dental Hospital, Fukuoka, Japan
⨯
Yoshitaka Hara,

Affiliation Nagasaki University Hospital, Attached School of Dentistry, Nagasaki, Japan
⨯
Yuichi Izumi,

Affiliation Kagoshima University Dental Hospital, Kagoshima, Japan
⨯
Takao Hirofuji,

Affiliation Fukuoka Dental College Hospital, Fukuoka, Japan
⨯
Enyu Imai,

Affiliation Osaka University Hospital, Suita, Japan
⨯
Masatoshi Omae,

Affiliation Izumisano Municipal Hospital, Rinku General Medical Center, Izumisano, Japan
⨯
Mitsuru Watanuki,

Affiliation Kaken Pharmaceutical Co., Ltd., Tokyo, Japan
⨯
[ ... ],
Shinya Murakami

* E-mail: ipshinya@dent.osaka-u.ac.jp

Affiliation Osaka University Dental Hospital, Suita, Japan
⨯
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Periodontal Tissue Regeneration Using Fibroblast Growth Factor -2: Randomized Controlled Phase II Clinical Trial

Masahiro Kitamura,
Keisuke Nakashima,
Yusuke Kowashi,
Takeo Fujii,
Hidetoshi Shimauchi,
Takashi Sasano,
Toshi Furuuchi,
Mitsuo Fukuda,
Toshihide Noguchi,
Toshiaki Shibutani

Published: July 2, 2008
https://doi.org/10.1371/journal.pone.0002611

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Alveolar bone
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