Binding to the Minor Groove of the Double-Strand, Tau Protein Prevents DNA from Damage by Peroxidation

Yan Wei; Mei-Hua Qu; Xing-Sheng Wang; Lan Chen; Dong-Liang Wang; Ying Liu; Qian Hua; Rong-Qiao He

doi:10.1371/journal.pone.0002600

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Open Access

Peer-reviewed

Research Article

Binding to the Minor Groove of the Double-Strand, Tau Protein Prevents DNA from Damage by Peroxidation

Yan Wei ,

Contributed equally to this work with: Yan Wei, Mei-Hua Qu

Affiliations State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, Graduate University of Chinese Academy of Sciences, Beijing, China
⨯
Mei-Hua Qu ,

Contributed equally to this work with: Yan Wei, Mei-Hua Qu

Affiliation State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
⨯
Xing-Sheng Wang,

Affiliation State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
⨯
Lan Chen,

Affiliation State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
⨯
Dong-Liang Wang,

Affiliations State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, Graduate University of Chinese Academy of Sciences, Beijing, China
⨯
Ying Liu,

Affiliation State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
⨯
Qian Hua,

Affiliations State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, School of Preclinical Medicine, Beijing University of Chinese Medicine, Beijing, China
⨯
Rong-Qiao He

* E-mail: herq@sun5.ibp.ac.cn

Affiliations State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, Graduate University of Chinese Academy of Sciences, Beijing, China
⨯

Binding to the Minor Groove of the Double-Strand, Tau Protein Prevents DNA from Damage by Peroxidation

Yan Wei,
Mei-Hua Qu,
Xing-Sheng Wang,
Lan Chen,
Dong-Liang Wang,
Ying Liu,
Qian Hua,
Rong-Qiao He

Published: July 2, 2008
https://doi.org/10.1371/journal.pone.0002600

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Tau protein
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DNA-binding proteins
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Electrophoretic mobility shift assay
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Polynucleotides
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DNA
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DNA damage
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Free radicals
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Protein interactions
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