Ubiquitination Is Required for Effective Replication of Coxsackievirus B3

Xiaoning Si; Guang Gao; Jerry Wong; Yahong Wang; Jingchun Zhang; Honglin Luo

doi:10.1371/journal.pone.0002585

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Open Access

Peer-reviewed

Research Article

Ubiquitination Is Required for Effective Replication of Coxsackievirus B3

Xiaoning Si,

Affiliation The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, Department of Pathology and Laboratory Medicine, University of British Columbia, Providence Heart + Lung Institute, St. Paul's Hospital, Vancouver, British Columbia, Canada
⨯
Guang Gao,

Affiliation The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, Department of Pathology and Laboratory Medicine, University of British Columbia, Providence Heart + Lung Institute, St. Paul's Hospital, Vancouver, British Columbia, Canada
⨯
Jerry Wong,

Affiliation The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, Department of Pathology and Laboratory Medicine, University of British Columbia, Providence Heart + Lung Institute, St. Paul's Hospital, Vancouver, British Columbia, Canada
⨯
Yahong Wang,

Affiliations The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, Department of Pathology and Laboratory Medicine, University of British Columbia, Providence Heart + Lung Institute, St. Paul's Hospital, Vancouver, British Columbia, Canada, Chinese Internal Medicine Laboratory, Department of Cardiology, Dongzhimen Hospital Affiliated with Beijing University of Chinese Medicine, Beijing, China
⨯
Jingchun Zhang,

Affiliation The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, Department of Pathology and Laboratory Medicine, University of British Columbia, Providence Heart + Lung Institute, St. Paul's Hospital, Vancouver, British Columbia, Canada
⨯
Honglin Luo

* E-mail: hluo@mrl.ubc.ca

Affiliation The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, Department of Pathology and Laboratory Medicine, University of British Columbia, Providence Heart + Lung Institute, St. Paul's Hospital, Vancouver, British Columbia, Canada
⨯

Ubiquitination Is Required for Effective Replication of Coxsackievirus B3

Xiaoning Si,
Guang Gao,
Jerry Wong,
Yahong Wang,
Jingchun Zhang,
Honglin Luo

Published: July 9, 2008
https://doi.org/10.1371/journal.pone.0002585

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Ubiquitination
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Viral replication
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Small interfering RNA
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Proteasomes
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Proteasome inhibitors
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HeLa cells
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Immunoprecipitation
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