Saturated Fatty Acids Modulate Cell Response to DNA Damage: Implication for Their Role in Tumorigenesis

Li Zeng; Guang-Zhi Wu; Kim Jee Goh; Yew Mun Lee; Chuo Chung Ng; Ang Ben You; Jianhe Wang; Deyong Jia; Aijun Hao; Qiang Yu; Baojie Li

doi:10.1371/journal.pone.0002329

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Open Access

Peer-reviewed

Research Article

Saturated Fatty Acids Modulate Cell Response to DNA Damage: Implication for Their Role in Tumorigenesis

Li Zeng,

Affiliation Cancer and Developmental Biology Division, Institute of Molecular and Cell Biology, Singapore, Republic of Singapore
⨯
Guang-Zhi Wu,

Affiliations Cancer and Developmental Biology Division, Institute of Molecular and Cell Biology, Singapore, Republic of Singapore, China-Japan Union Hospital, Jilin University, Changchun, Jilin, People's Republic of China
⨯
Kim Jee Goh,

Affiliation Cancer and Developmental Biology Division, Institute of Molecular and Cell Biology, Singapore, Republic of Singapore
⨯
Yew Mun Lee,

Affiliation Cancer and Developmental Biology Division, Institute of Molecular and Cell Biology, Singapore, Republic of Singapore
⨯
Chuo Chung Ng,

Affiliation Cancer and Developmental Biology Division, Institute of Molecular and Cell Biology, Singapore, Republic of Singapore
⨯
Ang Ben You,

Affiliation Cancer and Developmental Biology Division, Institute of Molecular and Cell Biology, Singapore, Republic of Singapore
⨯
Jianhe Wang,

Affiliation Cancer and Developmental Biology Division, Institute of Molecular and Cell Biology, Singapore, Republic of Singapore
⨯
Deyong Jia,

Affiliation The Key Laboratory of Experimental Teratology, Ministry of Education, Faculty of Medicine, Shandong University, Jinan, Shandong, People's Republic of China
⨯
Aijun Hao,

Affiliation The Key Laboratory of Experimental Teratology, Ministry of Education, Faculty of Medicine, Shandong University, Jinan, Shandong, People's Republic of China
⨯
Qiang Yu,

Affiliation Laboratory of Molecular Pharmacology, Genome Institute of Singapore, Singapore, Republic of Singapore
⨯
Baojie Li

* E-mail: libj@imcb.a-star.edu.sg

Affiliation Cancer and Developmental Biology Division, Institute of Molecular and Cell Biology, Singapore, Republic of Singapore
⨯

Saturated Fatty Acids Modulate Cell Response to DNA Damage: Implication for Their Role in Tumorigenesis

Li Zeng,
Guang-Zhi Wu,
Kim Jee Goh,
Yew Mun Lee,
Chuo Chung Ng,
Ang Ben You,
Jianhe Wang,
Deyong Jia,
Aijun Hao,
Qiang Yu

Published: June 4, 2008
https://doi.org/10.1371/journal.pone.0002329

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DNA damage
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Phosphorylation
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Fatty acids
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Breast cancer
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