A DNA Polymerase α Accessory Protein, Mcl1, Is Required for Propagation of Centromere Structures in Fission Yeast

Toyoaki Natsume; Yasuhiro Tsutsui; Takashi Sutani; Elaine M. Dunleavy; Alison L. Pidoux; Hiroshi Iwasaki; Katsuhiko Shirahige; Robin C. Allshire; Fumiaki Yamao

doi:10.1371/journal.pone.0002221

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Research Article

A DNA Polymerase α Accessory Protein, Mcl1, Is Required for Propagation of Centromere Structures in Fission Yeast

Toyoaki Natsume,

Current address: College of Life Sciences, University of Dundee, Dundee, United Kingdom

Affiliation Division of Mutagenesis, National Institute of Genetics, Mishima, Shizuoka, Japan
⨯
Yasuhiro Tsutsui ,

* E-mail: ytsutsui@lab.nig.ac.jp

Affiliation Division of Mutagenesis, National Institute of Genetics, Mishima, Shizuoka, Japan
⨯
Takashi Sutani,

Affiliation Laboratory of Genome Structure & Function, Center for Biological Resources and Informatics, Tokyo Institute of Technology, Yokohama, Kanagawa, Japan
⨯
Elaine M. Dunleavy,

Current address: Department of Chromatin Dynamics, Institut Curie, Section de Recherche, UMR 218-Pavillon Pasteur, Paris, France

Affiliation Wellcome Trust Centre for Cell Biology, Institute of Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, Scotland, United Kingdom
⨯
Alison L. Pidoux,

Affiliation Wellcome Trust Centre for Cell Biology, Institute of Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, Scotland, United Kingdom
⨯
Hiroshi Iwasaki,

Affiliation Division of Molecular and Cellular Biology, International Graduate School of Arts and Sciences, Yokohama City University, Yokohama, Kanagawa, Japan
⨯
Katsuhiko Shirahige,

Affiliation Laboratory of Genome Structure & Function, Center for Biological Resources and Informatics, Tokyo Institute of Technology, Yokohama, Kanagawa, Japan
⨯
Robin C. Allshire,

Affiliation Wellcome Trust Centre for Cell Biology, Institute of Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, Scotland, United Kingdom
⨯
Fumiaki Yamao

Affiliation Division of Mutagenesis, National Institute of Genetics, Mishima, Shizuoka, Japan
⨯

A DNA Polymerase α Accessory Protein, Mcl1, Is Required for Propagation of Centromere Structures in Fission Yeast

Toyoaki Natsume,
Yasuhiro Tsutsui,
Takashi Sutani,
Elaine M. Dunleavy,
Alison L. Pidoux,
Hiroshi Iwasaki,
Katsuhiko Shirahige,
Robin C. Allshire,
Fumiaki Yamao

Published: May 21, 2008
https://doi.org/10.1371/journal.pone.0002221

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DNA replication
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Centromeres
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Chromatin
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Histones
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Schizosaccharomyces pombe
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Synthesis phase
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Acetylation
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Heterochromatin
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