Automated Three-Dimensional Detection and Shape Classification of Dendritic Spines from Fluorescence Microscopy Images

Alfredo Rodriguez; Douglas B. Ehlenberger; Dara L. Dickstein; Patrick R. Hof; Susan L. Wearne

doi:10.1371/journal.pone.0001997

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Peer-reviewed

Research Article

Automated Three-Dimensional Detection and Shape Classification of Dendritic Spines from Fluorescence Microscopy Images

Alfredo Rodriguez,

Affiliations Department of Neuroscience, Mount Sinai School of Medicine, New York, New York, United States of America, Laboratory of Biomathematics, Mount Sinai School of Medicine, New York, New York, United States of America, Computational Neurobiology and Imaging Center, Mount Sinai School of Medicine, New York, New York, United States of America
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Douglas B. Ehlenberger,

Affiliations Department of Neuroscience, Mount Sinai School of Medicine, New York, New York, United States of America, Laboratory of Biomathematics, Mount Sinai School of Medicine, New York, New York, United States of America, Computational Neurobiology and Imaging Center, Mount Sinai School of Medicine, New York, New York, United States of America
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Dara L. Dickstein,

Affiliations Department of Neuroscience, Mount Sinai School of Medicine, New York, New York, United States of America, Computational Neurobiology and Imaging Center, Mount Sinai School of Medicine, New York, New York, United States of America
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Patrick R. Hof,

Affiliations Department of Neuroscience, Mount Sinai School of Medicine, New York, New York, United States of America, Computational Neurobiology and Imaging Center, Mount Sinai School of Medicine, New York, New York, United States of America
⨯
Susan L. Wearne

* E-mail: susan.wearne@mssm.edu

Affiliations Department of Neuroscience, Mount Sinai School of Medicine, New York, New York, United States of America, Laboratory of Biomathematics, Mount Sinai School of Medicine, New York, New York, United States of America, Computational Neurobiology and Imaging Center, Mount Sinai School of Medicine, New York, New York, United States of America
⨯

Automated Three-Dimensional Detection and Shape Classification of Dendritic Spines from Fluorescence Microscopy Images

Alfredo Rodriguez,
Douglas B. Ehlenberger,
Dara L. Dickstein,
Patrick R. Hof,
Susan L. Wearne

Published: April 23, 2008
https://doi.org/10.1371/journal.pone.0001997

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28 Apr 2008
18:41 GMT
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Publisher's Note: Correction to Academic Editor's name Posted by PLOS_ONE_Group on 28 Apr 2008 at 18:41 GMT
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24 Apr 2008
13:56 GMT
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Referee comments: Referee 2 Posted by PLOS_ONE_Group on 24 Apr 2008 at 13:56 GMT

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Neuronal dendrites
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Neck
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Dendritic structure
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Neuronal morphology
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Head
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Confocal laser microscopy
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Imaging techniques
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