Safety and Immunogenicity of a Malaria Vaccine, Plasmodium falciparum AMA-1/MSP-1 Chimeric Protein Formulated in Montanide ISA 720 in Healthy Adults

Jinhong Hu; Zhihui Chen; Jun Gu; Mobin Wan; Qian Shen; Marie-Paule Kieny; Jia He; Zhen Li; Qingfeng Zhang; Zarifah Hussain Reed; Yongmei Zhu; Wenjie Li; Yang Cao; Li Qu; Zhifang Cao; Qiang Wang; Haitao Liu; Xuegong Pan; Xiudong Huang; Dongmei Zhang; Xiangyang Xue; Weiqing Pan

doi:10.1371/journal.pone.0001952

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Open Access

Peer-reviewed

Research Article

Safety and Immunogenicity of a Malaria Vaccine, Plasmodium falciparum AMA-1/MSP-1 Chimeric Protein Formulated in Montanide ISA 720 in Healthy Adults

Jinhong Hu,

Affiliation Changhai Hospital, Second Military Medical University, Shanghai, China
⨯
Zhihui Chen,

Affiliation Changhai Hospital, Second Military Medical University, Shanghai, China
⨯
Jun Gu,

Affiliation Changhai Hospital, Second Military Medical University, Shanghai, China
⨯
Mobin Wan,

Affiliation Changhai Hospital, Second Military Medical University, Shanghai, China
⨯
Qian Shen,

Affiliation Changhai Hospital, Second Military Medical University, Shanghai, China
⨯
Marie-Paule Kieny,

Affiliation Initiative for Vaccine Research, World Health Organization, Geneva, Switzerland
⨯
Jia He,

Affiliation Department of Statistics, Second Military Medical University, Shanghai, China
⨯
Zhen Li,

Affiliation Changhai Hospital, Second Military Medical University, Shanghai, China
⨯
Qingfeng Zhang,

Affiliation Department of Pathogen Biology and State Key Laboratory of Medical Immunology, Second Military Medical University, Shanghai, China
⨯
Zarifah Hussain Reed,

Affiliation Initiative for Vaccine Research, World Health Organization, Geneva, Switzerland
⨯
Yongmei Zhu,

Affiliation Changhai Hospital, Second Military Medical University, Shanghai, China
⨯
Wenjie Li,

Affiliation Changhai Hospital, Second Military Medical University, Shanghai, China
⨯
Yang Cao,

Affiliation Department of Statistics, Second Military Medical University, Shanghai, China
⨯
Li Qu,

Affiliation Department of Pathogen Biology and State Key Laboratory of Medical Immunology, Second Military Medical University, Shanghai, China
⨯
Zhifang Cao,

Affiliation Shanghai Wanxing Biopharmaceuticals Co., Ltd., Shanghai, China
⨯
Qiang Wang,

Affiliation Shanghai Wanxing Biopharmaceuticals Co., Ltd., Shanghai, China
⨯
Haitao Liu,

Affiliation Shanghai Wanxing Biopharmaceuticals Co., Ltd., Shanghai, China
⨯
Xuegong Pan,

Affiliation Shanghai Wanxing Biopharmaceuticals Co., Ltd., Shanghai, China
⨯
Xiudong Huang,

Affiliation Shanghai Wanxing Biopharmaceuticals Co., Ltd., Shanghai, China
⨯
Dongmei Zhang,

Affiliation Department of Pathogen Biology and State Key Laboratory of Medical Immunology, Second Military Medical University, Shanghai, China
⨯
Xiangyang Xue,

Affiliation Department of Pathogen Biology and State Key Laboratory of Medical Immunology, Second Military Medical University, Shanghai, China
⨯
[ ... ],
Weiqing Pan

*To whom correspondence should be addressed. E-mail: wqpan0912@yahoo.com.cn

Affiliation Department of Pathogen Biology and State Key Laboratory of Medical Immunology, Second Military Medical University, Shanghai, China
⨯
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Safety and Immunogenicity of a Malaria Vaccine, Plasmodium falciparum AMA-1/MSP-1 Chimeric Protein Formulated in Montanide ISA 720 in Healthy Adults

Jinhong Hu,
Zhihui Chen,
Jun Gu,
Mobin Wan,
Qian Shen,
Marie-Paule Kieny,
Jia He,
Zhen Li,
Qingfeng Zhang,
Zarifah Hussain Reed

Published: April 9, 2008
https://doi.org/10.1371/journal.pone.0001952

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