Control of Muscle Mitochondria by Insulin Entails Activation of Akt2-mtNOS Pathway: Implications for the Metabolic Syndrome

• Paola Finocchietto,

  Affiliations Laboratory of Oxygen Metabolism, University Hospital, Buenos Aires, Argentina, Department of Medicine, University Hospital, University of Buenos Aires, Buenos Aires, Argentina

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• Fernando Barreyro,

  Affiliations Laboratory of Oxygen Metabolism, University Hospital, Buenos Aires, Argentina, Department of Medicine, University Hospital, University of Buenos Aires, Buenos Aires, Argentina

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• Silvia Holod,

  Affiliations Laboratory of Oxygen Metabolism, University Hospital, Buenos Aires, Argentina, Department of Clinical Biochemistry, School of Pharmacy and Biochemistry, University Hospital, University of Buenos Aires, Buenos Aires, Argentina

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• Jorge Peralta,

  Affiliations Laboratory of Oxygen Metabolism, University Hospital, Buenos Aires, Argentina, Department of Medicine, University Hospital, University of Buenos Aires, Buenos Aires, Argentina

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• María C. Franco,

  Affiliation Laboratory of Oxygen Metabolism, University Hospital, Buenos Aires, Argentina

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• Carlos Méndez,

  Affiliation Department of Human Biochemistry, School of Medicine, University of Buenos Aires, Buenos Aires, Argentina

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• Daniela P. Converso,

  Affiliation Laboratory of Oxygen Metabolism, University Hospital, Buenos Aires, Argentina

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• Alvaro Estévez,

  Affiliation Burke Medical Research Institute, Cornell University, Ithaca, New York, United States of America

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• Maria C. Carreras,

  Affiliations Laboratory of Oxygen Metabolism, University Hospital, Buenos Aires, Argentina, Department of Clinical Biochemistry, School of Pharmacy and Biochemistry, University Hospital, University of Buenos Aires, Buenos Aires, Argentina

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• Juan J. Poderoso

  *To whom correspondence should be addressed. E-mail: jpoderos@fmed.uba.ar

  Affiliations Laboratory of Oxygen Metabolism, University Hospital, Buenos Aires, Argentina, Department of Medicine, University Hospital, University of Buenos Aires, Buenos Aires, Argentina

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