Rapid Diagnosis of Smear-Negative Tuberculosis Using Immunology and Microbiology with Induced Sputum in HIV-Infected and Uninfected Individuals

Ronan A. M. Breen; Gareth A. D. Hardy; Felicity M. R. Perrin; Sara Lear; Sabine Kinloch; Colette J. Smith; Ian Cropley; George Janossy; Marc C. I. Lipman

doi:10.1371/journal.pone.0001335

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Open Access

Peer-reviewed

Research Article

Rapid Diagnosis of Smear-Negative Tuberculosis Using Immunology and Microbiology with Induced Sputum in HIV-Infected and Uninfected Individuals

Ronan A. M. Breen ,

*To whom correspondence should be addressed. E-mail: ronan.breen@gstt.nhs.uk

Affiliations Department of Immunology, Royal Free & University College Medical School, London, United Kingdom, Departments of Thoracic and HIV Medicine, Royal Free Hospital London, London, United Kingdom
⨯
Gareth A. D. Hardy,

Affiliation Department of Immunology, Royal Free & University College Medical School, London, United Kingdom
⨯
Felicity M. R. Perrin,

Affiliations Departments of Thoracic and HIV Medicine, Royal Free Hospital London, London, United Kingdom, Centre for Medical Microbiology, Royal Free & University College Medical School, London, United Kingdom
⨯
Sara Lear,

Affiliation Department of Immunology, Royal Free & University College Medical School, London, United Kingdom
⨯
Sabine Kinloch,

Affiliations Department of Immunology, Royal Free & University College Medical School, London, United Kingdom, Departments of Thoracic and HIV Medicine, Royal Free Hospital London, London, United Kingdom
⨯
Colette J. Smith,

Affiliation Department of Primary Care and Population Science, Royal Free & University College Medical School, London, United Kingdom
⨯
Ian Cropley,

Affiliation Departments of Thoracic and HIV Medicine, Royal Free Hospital London, London, United Kingdom
⨯
George Janossy,

Affiliation Department of Immunology, Royal Free & University College Medical School, London, United Kingdom
⨯
Marc C. I. Lipman

Affiliation Departments of Thoracic and HIV Medicine, Royal Free Hospital London, London, United Kingdom
⨯

Rapid Diagnosis of Smear-Negative Tuberculosis Using Immunology and Microbiology with Induced Sputum in HIV-Infected and Uninfected Individuals

Ronan A. M. Breen,
Gareth A. D. Hardy,
Felicity M. R. Perrin,
Sara Lear,
Sabine Kinloch,
Colette J. Smith,
Ian Cropley,
George Janossy,
Marc C. I. Lipman

Published: December 19, 2007
https://doi.org/10.1371/journal.pone.0001335

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Tuberculosis
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Tuberculosis diagnosis and management
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Mycobacterium tuberculosis
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Enzyme-linked immunoassays
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