Evidence for Positive Selection in the C-terminal Domain of the Cholesterol Metabolism Gene PCSK9 Based on Phylogenetic Analysis in 14 Primate Species

Open Access

Peer-reviewed

Research Article

Keyue Ding,

Affiliation Division of Cardiovascular Diseases, Mayo Clinic and Foundation, Rochester, Minnesota, United States of America
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Samantha J. McDonough,

Affiliation Division of Cardiovascular Diseases, Mayo Clinic and Foundation, Rochester, Minnesota, United States of America
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Iftikhar J. Kullo

*To whom correspondence should be addressed. E-mail: kullo.iftikhar@mayo.edu

Affiliation Division of Cardiovascular Diseases, Mayo Clinic and Foundation, Rochester, Minnesota, United States of America
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Primates
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Cholesterol
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Phylogenetic analysis
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Orangutans
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New World monkeys
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Nonsense mutation
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Animal phylogenetics
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Evolutionary genetics
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