Constraint-Based Modeling and Kinetic Analysis of the Smad Dependent TGF-β Signaling Pathway

Open Access

Peer-reviewed

Research Article

Zhike Zi,

Affiliation Computational Systems Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany
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Edda Klipp

*To whom correspondence should be addressed. E-mail: klipp@molgen.mpg.de

Affiliations Computational Systems Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany, Theoretical Biophysics, Humboldt University Berlin, Institute for Biology, Berlin, Germany
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Phosphorylation
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Endocytosis
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SMAD signaling
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Simulation and modeling
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Endosomes
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Membrane receptor signaling
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TGF-beta signaling cascade
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Dose prediction methods
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