High-Threshold Mechanosensitive Ion Channels Blocked by a Novel Conopeptide Mediate Pressure-Evoked Pain

• Liam J. Drew,

  Current address: Department of Physiology and Cellular Biophysics, Columbia University, New York, New York, United States of America

  Affiliation Department of Biology, University College London, London, United Kingdom

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• Francois Rugiero,

  Affiliation Department of Biology, University College London, London, United Kingdom

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• Paolo Cesare,

  Affiliation Fondazione Santa Lucia, Centro Europeo di Ricerca sul Cervello, Rome, Italy

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• Jonathan E. Gale,

  Affiliation Centre for Auditory Research, University College London Ear Institute, London, United Kingdom

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• Bjarke Abrahamsen,

  Affiliation Department of Biology, University College London, London, United Kingdom

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• Sarah Bowden,

  Affiliation Ionix Pharmaceuticals Ltd, Cambridge, United Kingdom

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• Sebastian Heinzmann,

  Affiliation Department of Biology, University College London, London, United Kingdom

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• Michelle Robinson,

  Affiliation Department of Biology, University College London, London, United Kingdom

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• Andreas Brust,

  Affiliation Xenome Ltd, Indooroopilly, Queensland, Australia

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• Barbara Colless,

  Affiliation Xenome Ltd, Indooroopilly, Queensland, Australia

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• Richard J. Lewis,

  Affiliations Xenome Ltd, Indooroopilly, Queensland, Australia, Institute for Molecular Bioscience and School of Biomedical Sciences, The University of Queensland, St. Lucia, Queensland, Australia

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• John N. Wood

  *To whom correspondence should be addressed. E-mail: j.wood@ucl.ac.uk

  Affiliation Department of Biology, University College London, London, United Kingdom

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