Breakage-Reunion Domain of Streptococcus pneumoniae Topoisomerase IV: Crystal Structure of a Gram-Positive Quinolone Target

• Ivan Laponogov ,

  Contributed equally to this work with: Ivan Laponogov, Dennis A. Veselkov, Maninder K. Sohi, Xiao-Su Pan

  Affiliation Randall Division of Cell and Molecular Biophysics, School of Biomedical and Health Sciences, King's College London, London, United Kindgom

  ⨯
• Dennis A. Veselkov ,

  Contributed equally to this work with: Ivan Laponogov, Dennis A. Veselkov, Maninder K. Sohi, Xiao-Su Pan

  Affiliation Randall Division of Cell and Molecular Biophysics, School of Biomedical and Health Sciences, King's College London, London, United Kindgom

  ⨯
• Maninder K. Sohi ,

  Contributed equally to this work with: Ivan Laponogov, Dennis A. Veselkov, Maninder K. Sohi, Xiao-Su Pan

  Affiliation Randall Division of Cell and Molecular Biophysics, School of Biomedical and Health Sciences, King's College London, London, United Kindgom

  ⨯
• Xiao-Su Pan ,

  Contributed equally to this work with: Ivan Laponogov, Dennis A. Veselkov, Maninder K. Sohi, Xiao-Su Pan

  Affiliation Molecular Genetics Group, Molecular and Metabolic Signalling Centre, Division of Basic Medical Sciences, St. George's, University of London, London, United Kindgom

  ⨯
• Aniruddha Achari,

  Current address: Raytheon IS, EM10, NASA Marshall Space Flight Center, Huntsville, Alabama, United States of America

  Affiliation Randall Division of Cell and Molecular Biophysics, School of Biomedical and Health Sciences, King's College London, London, United Kindgom

  ⨯
• Cheng Yang,

  Affiliation Rigaku Americas Corporation, The Woodlands, Texas, United States of America

  ⨯
• Joseph D. Ferrara,

  Affiliation Rigaku Americas Corporation, The Woodlands, Texas, United States of America

  ⨯
• L. Mark Fisher ,

  *To whom correspondence should be addressed. E-mail: mark.sanderson@kcl.ac.uk (MS); lfisher@sgul.ac.uk (LF)

  Affiliation Molecular Genetics Group, Molecular and Metabolic Signalling Centre, Division of Basic Medical Sciences, St. George's, University of London, London, United Kindgom

  ⨯
• Mark R. Sanderson

  *To whom correspondence should be addressed. E-mail: mark.sanderson@kcl.ac.uk (MS); lfisher@sgul.ac.uk (LF)

  Affiliation Randall Division of Cell and Molecular Biophysics, School of Biomedical and Health Sciences, King's College London, London, United Kindgom

  ⨯