Chloroquine Resistant Plasmodium vivax: In Vitro Characterisation and Association with Molecular Polymorphisms

Rossarin Suwanarusk; Bruce Russell; Marina Chavchich; Ferryanto Chalfein; Enny Kenangalem; Varakorn Kosaisavee; Budi Prasetyorini; Kim A. Piera; Marion Barends; Alan Brockman; Usa Lek-Uthai; Nicholas M. Anstey; Emiliana Tjitra; François Nosten; Qin Cheng; Ric N. Price

doi:10.1371/journal.pone.0001089

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Research Article

Chloroquine Resistant Plasmodium vivax: In Vitro Characterisation and Association with Molecular Polymorphisms

Rossarin Suwanarusk ,

Contributed equally to this work with: Rossarin Suwanarusk, Bruce Russell

Affiliation International Health Program, Infectious Diseases Division, Menzies School of Health Research and Charles Darwin University, Darwin, Australia
⨯
Bruce Russell ,

Contributed equally to this work with: Rossarin Suwanarusk, Bruce Russell

Affiliation International Health Program, Infectious Diseases Division, Menzies School of Health Research and Charles Darwin University, Darwin, Australia
⨯
Marina Chavchich,

Affiliation Department of Drug Resistance and Diagnostics, Australian Army Malaria Institute, Brisbane, Australia
⨯
Ferryanto Chalfein,

Affiliation National Institute of Health Research and Development and Menzies School of Health Malaria Research Program, Timika, Indonesia
⨯
Enny Kenangalem,

Affiliations National Institute of Health Research and Development and Menzies School of Health Malaria Research Program, Timika, Indonesia, District Ministry of Health, Timika, Papua, Indonesia
⨯
Varakorn Kosaisavee,

Affiliation Department of Parasitology, Faculty of Public Health, Mahidol University, Bangkok, Thailand
⨯
Budi Prasetyorini,

Affiliation National Institute of Health Research and Development, Ministry of Health, Jakarta, Indonesia
⨯
Kim A. Piera,

Affiliation International Health Program, Infectious Diseases Division, Menzies School of Health Research and Charles Darwin University, Darwin, Australia
⨯
Marion Barends,

Affiliation Shoklo Malaria Research Unit, Mae Sod, Tak Province, Thailand
⨯
Alan Brockman,

Affiliation International Health Program, Infectious Diseases Division, Menzies School of Health Research and Charles Darwin University, Darwin, Australia
⨯
Usa Lek-Uthai,

Affiliation Department of Parasitology, Faculty of Public Health, Mahidol University, Bangkok, Thailand
⨯
Nicholas M. Anstey,

Affiliation International Health Program, Infectious Diseases Division, Menzies School of Health Research and Charles Darwin University, Darwin, Australia
⨯
Emiliana Tjitra,

Affiliation National Institute of Health Research and Development, Ministry of Health, Jakarta, Indonesia
⨯
François Nosten,

Affiliations Faculty of Tropical Medicine, Mahidol University, Bangkok Thailand, Shoklo Malaria Research Unit, Mae Sod, Tak Province, Thailand
⨯
Qin Cheng,

Affiliation Department of Drug Resistance and Diagnostics, Australian Army Malaria Institute, Brisbane, Australia
⨯
[ ... ],
Ric N. Price

*To whom correspondence should be addressed. E-mail: rnp@menzies.edu.au

Affiliations International Health Program, Infectious Diseases Division, Menzies School of Health Research and Charles Darwin University, Darwin, Australia, Centre for Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Oxford, United Kingdom
⨯
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Chloroquine Resistant Plasmodium vivax: In Vitro Characterisation and Association with Molecular Polymorphisms

Rossarin Suwanarusk,
Bruce Russell,
Marina Chavchich,
Ferryanto Chalfein,
Enny Kenangalem,
Varakorn Kosaisavee,
Budi Prasetyorini,
Kim A. Piera,
Marion Barends,
Alan Brockman

Published: October 31, 2007
https://doi.org/10.1371/journal.pone.0001089

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A step forward in understanding P. vivax

Posted by Colins on 31 Oct 2007 at 17:39 GMT

This paper by Suwanarusk, Russell and colleagues takes a big step forwards towards a reliable approach for investigation of chloroquine resistance in the malaria parasite Plasmodium vivax.

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Chloroquine Resistant Plasmodium vivax: In Vitro Characterisation and Association with Molecular Polymorphisms

Chloroquine Resistant Plasmodium vivax: In Vitro Characterisation and Association with Molecular Polymorphisms

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A step forward in understanding P. vivax

Posted by Colins on 31 Oct 2007 at 17:39 GMT