Nestin Is Essential for Zebrafish Brain and Eye Development through Control of Progenitor Cell Apoptosis

Hua-Ling Chen; Chiou-Hwa Yuh; Kenneth K. Wu

doi:10.1371/journal.pone.0009318

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Open Access

Peer-reviewed

Research Article

Nestin Is Essential for Zebrafish Brain and Eye Development through Control of Progenitor Cell Apoptosis

Hua-Ling Chen,

Affiliation Institute of Cellular and System Medicine, National Health Research Institutes, Zhunan, Taiwan
⨯
Chiou-Hwa Yuh,

Affiliation Division of Molecular and Genomic Medicine, National Health Research Institutes, Zhunan, Taiwan
⨯
Kenneth K. Wu

* E-mail: kkgo@nhri.org.tw

Affiliation Institute of Cellular and System Medicine, National Health Research Institutes, Zhunan, Taiwan
⨯

Nestin Is Essential for Zebrafish Brain and Eye Development through Control of Progenitor Cell Apoptosis

Hua-Ling Chen,
Chiou-Hwa Yuh,
Kenneth K. Wu

Published: February 19, 2010
https://doi.org/10.1371/journal.pone.0009318

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Toxic morpholino alert

Posted by SGERETY on 30 Jun 2010 at 11:01 GMT

Any zebrafish paper NOT citing Robu et al on the toxicity of morpholinos and non-specific p53 dependent apoptosis induced should NOT be published. It is a shame that PLOS ONE editorial board and reviewers overlook this essential control, and are unaware of the pitfalls of MO technology. Especially worrying since Robu et al is a PLOS paper :PLoS Genet. 2007 May 25;3(5):e78

No competing interests declared.

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Nestin
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Nestin Is Essential for Zebrafish Brain and Eye Development through Control of Progenitor Cell Apoptosis

Nestin Is Essential for Zebrafish Brain and Eye Development through Control of Progenitor Cell Apoptosis

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Toxic morpholino alert

Posted by SGERETY on 30 Jun 2010 at 11:01 GMT