A Hepatic Protein, Fetuin-A, Occupies a Protective Role in Lethal Systemic Inflammation

Wei Li; Shu Zhu; Jianhua Li; Yan Huang; Zhou Rongrong; Xuegong Fan; Huan Yang; Xing Gong; N. Tony Eissa; Willi Jahnen-Dechent; Ping Wang; Kevin J. Tracey; Andrew E. Sama; Haichao Wang

doi:10.1371/journal.pone.0016945

Loading metrics

Open Access

Peer-reviewed

Research Article

A Hepatic Protein, Fetuin-A, Occupies a Protective Role in Lethal Systemic Inflammation

Wei Li ,

Contributed equally to this work with: Wei Li, Shu Zhu

Affiliations The Feinstein Institute for Medical Research, Manhasset, New York, United States of America, Department of Emergency Medicine, North Shore University Hospital, Manhasset, New York, United States of America
⨯
Shu Zhu ,

Contributed equally to this work with: Wei Li, Shu Zhu

Affiliations The Feinstein Institute for Medical Research, Manhasset, New York, United States of America, Department of Emergency Medicine, North Shore University Hospital, Manhasset, New York, United States of America
⨯
Jianhua Li,

Affiliation The Feinstein Institute for Medical Research, Manhasset, New York, United States of America
⨯
Yan Huang,

Affiliations The Feinstein Institute for Medical Research, Manhasset, New York, United States of America, Department of Infectious Diseases, Xiangya Hospital, Central South University, Changsha, People's Republic of China
⨯
Zhou Rongrong,

Affiliations The Feinstein Institute for Medical Research, Manhasset, New York, United States of America, Department of Infectious Diseases, Xiangya Hospital, Central South University, Changsha, People's Republic of China
⨯
Xuegong Fan,

Affiliation Department of Infectious Diseases, Xiangya Hospital, Central South University, Changsha, People's Republic of China
⨯
Huan Yang,

Affiliation The Feinstein Institute for Medical Research, Manhasset, New York, United States of America
⨯
Xing Gong,

Affiliation Pulmonary Critical Care and Sleep Medicine Section, Baylor College of Medicine, Houston, Texas, United States of America
⨯
N. Tony Eissa,

Affiliation Pulmonary Critical Care and Sleep Medicine Section, Baylor College of Medicine, Houston, Texas, United States of America
⨯
Willi Jahnen-Dechent,

Affiliation Department of Biomedical Engineering, Biointerface Laboratory, RWTH Aachen University Hospital, Aachen, Germany
⨯
Ping Wang,

Affiliation The Feinstein Institute for Medical Research, Manhasset, New York, United States of America
⨯
Kevin J. Tracey,

Affiliation The Feinstein Institute for Medical Research, Manhasset, New York, United States of America
⨯
Andrew E. Sama,

Affiliations The Feinstein Institute for Medical Research, Manhasset, New York, United States of America, Department of Emergency Medicine, North Shore University Hospital, Manhasset, New York, United States of America
⨯
Haichao Wang

* E-mail: hwang@nshs.edu

Affiliations The Feinstein Institute for Medical Research, Manhasset, New York, United States of America, Department of Emergency Medicine, North Shore University Hospital, Manhasset, New York, United States of America
⨯

A Hepatic Protein, Fetuin-A, Occupies a Protective Role in Lethal Systemic Inflammation

Wei Li,
Shu Zhu,
Jianhua Li,
Yan Huang,
Zhou Rongrong,
Xuegong Fan,
Huan Yang,
Xing Gong,
N. Tony Eissa,
Willi Jahnen-Dechent

Published: February 8, 2011
https://doi.org/10.1371/journal.pone.0016945

Reader Comments

Post a new comment on this article

Publisher's Note: Minor correction to heading

Posted by PLOS_ONE_Group on 17 Feb 2011 at 00:11 GMT

Visualization of LC3-containing cytoplasmic vesicles (autophagosomes)
http://plosone.org/article/info:doi/10.1371/journal.pone.0016945#article1.body1.sec4.sec5.sec1.p1

The subheading "Visualization of LC3-containing cytoplasmic vesicles (autophagosomes)" should be a second-level heading rather than a third-level heading.

No competing interests declared.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Endotoxemia
Is the Subject Area "Endotoxemia" applicable to this article?

Thanks for your feedback.
Sepsis
Is the Subject Area "Sepsis" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Macrophages
Is the Subject Area "Macrophages" applicable to this article?

Thanks for your feedback.
Cytoplasmic staining
Is the Subject Area "Cytoplasmic staining" applicable to this article?

Thanks for your feedback.
Inflammation
Is the Subject Area "Inflammation" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.
Gel filtration
Is the Subject Area "Gel filtration" applicable to this article?

Thanks for your feedback.

A Hepatic Protein, Fetuin-A, Occupies a Protective Role in Lethal Systemic Inflammation

A Hepatic Protein, Fetuin-A, Occupies a Protective Role in Lethal Systemic Inflammation

Reader Comments

Post Your Discussion Comment

Why should this posting be reviewed?

Thank You!

Publisher's Note: Minor correction to heading

Posted by PLOS_ONE_Group on 17 Feb 2011 at 00:11 GMT