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Open Access
Peer-reviewed
Research Article
Lack of Innate Interferon Responses during SARS Coronavirus Infection in a Vaccination and Reinfection Ferret Model
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Mark J. Cameron,
Affiliations Division of Experimental Therapeutics, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada, University of Toronto, Toronto, Ontario, Canada
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Alyson A. Kelvin,
Affiliation Immune Diagnostics & Research, Toronto, Ontario, Canada
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Alberto J. Leon,
Affiliations Division of Experimental Therapeutics, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada, International Institute of Infection and Immunity, Shantou University Medical College, Shantou, Guangdong, China
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Cheryl M. Cameron,
Affiliations Division of Experimental Therapeutics, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada, University of Toronto, Toronto, Ontario, Canada
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Longsi Ran,
Affiliation Division of Experimental Therapeutics, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada
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Luoling Xu,
Affiliation Division of Experimental Therapeutics, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada
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Yong-Kyu Chu,
Affiliation Department of Biochemistry and Molecular Biology, Southern Research Institute, Birmingham, Alabama, United States of America
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Ali Danesh,
Affiliations Division of Experimental Therapeutics, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada, University of Toronto, Toronto, Ontario, Canada, Department of Immunology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
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Yuan Fang,
Affiliations Division of Experimental Therapeutics, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada, University of Toronto, Toronto, Ontario, Canada, Department of Immunology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
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Qianjun Li,
Affiliation Department of Biochemistry and Molecular Biology, Southern Research Institute, Birmingham, Alabama, United States of America
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Austin Anderson,
Affiliation Department of Biochemistry and Molecular Biology, Southern Research Institute, Birmingham, Alabama, United States of America
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Ronald C. Couch,
Affiliation Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America
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Stephane G. Paquette,
Affiliations Division of Experimental Therapeutics, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada, University of Toronto, Toronto, Ontario, Canada, Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
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Ndingsa G. Fomukong,
Affiliation Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America
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Otfried Kistner,
Affiliation Baxter Innovations GmbH, Vienna, Austria
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Manfred Lauchart,
Affiliation Baxter Innovations GmbH, Vienna, Austria
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Thomas Rowe,
Affiliations Division of Experimental Therapeutics, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada, University of Toronto, Toronto, Ontario, Canada
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Kevin S. Harrod,
Affiliation Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America
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Colleen B. Jonsson,
Affiliation Center for Predictive Medicine, Louisville, Kentucky, United States of America
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David J. Kelvin
* E-mail: dkelvin@uhnres.utoronto.ca
Affiliations Division of Experimental Therapeutics, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada, University of Toronto, Toronto, Ontario, Canada, Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada, Department of Immunology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada, International Institute of Infection and Immunity, Shantou University Medical College, Shantou, Guangdong, China, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America, Sezione di Microbiologia Sperimentale e Clinica, Dipartimento di Scienze Biomediche, Università degli Studi di Sassari, Sassari, Italy
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Lack of Innate Interferon Responses during SARS Coronavirus Infection in a Vaccination and Reinfection Ferret Model
- Mark J. Cameron,
- Alyson A. Kelvin,
- Alberto J. Leon,
- Cheryl M. Cameron,
- Longsi Ran,
- Luoling Xu,
- Yong-Kyu Chu,
- Ali Danesh,
- Yuan Fang,
- Qianjun Li
- Published: September 24, 2012
- https://doi.org/10.1371/journal.pone.0045842