Transplantation of Adult Mouse iPS Cell-Derived Photoreceptor Precursors Restores Retinal Structure and Function in Degenerative Mice

Budd A. Tucker; In-Hyun Park; Sara D. Qi; Henry J. Klassen; Caihui Jiang; Jing Yao; Stephen Redenti; George Q. Daley; Michael J. Young

doi:10.1371/journal.pone.0018992

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Peer-reviewed

Research Article

Transplantation of Adult Mouse iPS Cell-Derived Photoreceptor Precursors Restores Retinal Structure and Function in Degenerative Mice

Budd A. Tucker ,

* E-mail: budd-tucker@uiowa.edu

Affiliation Department of Ophthalmology, Institute for Vision Research, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America
⨯
In-Hyun Park,

Affiliation Division of Pediatric Hematology/Oncology, Children's Hospital Boston and Dana Farber Cancer Institute, Boston, Massachusetts, United States of America
⨯
Sara D. Qi,

Affiliation Department of Ophthalmology, Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Henry J. Klassen,

Affiliation Department of Ophthalmology, School of Medicine, Gavin Herbert Eye Institute, University of California Irvine, Orange, California, United States of America
⨯
Caihui Jiang,

Affiliation Department of Ophthalmology, Institute for Vision Research, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America
⨯
Jing Yao,

Affiliations Department of Ophthalmology, Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Ophthalmology, Eye&ENT Hospital, Shanghai Medical School, Fudan University, Shanghai, China
⨯
Stephen Redenti,

Affiliation Department of Ophthalmology, Institute for Vision Research, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America
⨯
George Q. Daley,

Affiliations Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America, Manton Center for Orphan Disease Research, Harvard Stem Cell Institute, Howard Hughes Medical Institute, Children's Hospital Boston, Boston, Massachusetts, United States of America
⨯
Michael J. Young

Affiliation Department of Ophthalmology, Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts, United States of America
⨯

Transplantation of Adult Mouse iPS Cell-Derived Photoreceptor Precursors Restores Retinal Structure and Function in Degenerative Mice

Budd A. Tucker,
In-Hyun Park,
Sara D. Qi,
Henry J. Klassen,
Caihui Jiang,
Jing Yao,
Stephen Redenti,
George Q. Daley,
Michael J. Young

Published: April 29, 2011
https://doi.org/10.1371/journal.pone.0018992

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Media Coverage of This Article

Posted by PLOS_ONE_Group on 25 Aug 2011 at 13:36 GMT

The following articles represent some of the media coverage that has occurred for this paper:

Publication: Irv Arons' Journal
Title: “Irv Arons' Journal: Stem Cells in Ophthalmology Update 7: Research Studies with Induced Pluripotent Stem Cells Suggest Opposite Results”
http://irvaronsjournal.bl...

Publication: sify.com
Title: “Scientists re-grow retinas, restore vision using skin`s stem cells”
http://www.sify.com/news/...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLoS ONE Staff

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Transplantation of Adult Mouse iPS Cell-Derived Photoreceptor Precursors Restores Retinal Structure and Function in Degenerative Mice

Transplantation of Adult Mouse iPS Cell-Derived Photoreceptor Precursors Restores Retinal Structure and Function in Degenerative Mice

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Media Coverage of This Article

Posted by PLOS_ONE_Group on 25 Aug 2011 at 13:36 GMT