Effect of Statin Use on Outcomes of Adults with Candidemia

Guillermo Cuervo; Carolina Garcia-Vidal; Marcio Nucci; Francesc Puchades; Mario Fernández-Ruiz; Analía Mykietiuk; Adriana Manzur; Carlota Gudiol; Javier Pemán; Diego Viasus; Josefina Ayats; Jordi Carratalà

doi:10.1371/journal.pone.0077317

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Open Access

Peer-reviewed

Research Article

Effect of Statin Use on Outcomes of Adults with Candidemia

Guillermo Cuervo,

Affiliation Hospital Universitari de Bellvitge, IDIBELL (Institut D’investigació Biomèdica de Bellvitge), Universitat de Barcelona, Barcelona, Spain
⨯
Carolina Garcia-Vidal ,

* E-mail: carolgv75@hotmail.com

Affiliation Hospital Universitari de Bellvitge, IDIBELL (Institut D’investigació Biomèdica de Bellvitge), Universitat de Barcelona, Barcelona, Spain
⨯
Marcio Nucci,

Affiliation University Hospital, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
⨯
Francesc Puchades,

Affiliation Hospital Universitari i Politecnic “La Fe”, Valencia, Spain
⨯
Mario Fernández-Ruiz,

Affiliation Hospital Universitario “12 de Octubre”, Instituto de Investigación Hospital 12 de Octubre (i+12), Madrid, Spain
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Analía Mykietiuk,

Affiliation Hospital Interzonal de Agudos “Dr. Rodolfo Rossi”, La Plata, Argentina
⨯
Adriana Manzur,

Affiliation Hospital “Dr. Guillermo Rawson”, San Juan, Argentina
⨯
Carlota Gudiol,

Affiliation Hospital Universitari de Bellvitge, IDIBELL (Institut D’investigació Biomèdica de Bellvitge), Universitat de Barcelona, Barcelona, Spain
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Javier Pemán,

Affiliation Hospital Universitari i Politecnic “La Fe”, Valencia, Spain
⨯
Diego Viasus,

Affiliation Hospital Universitari de Bellvitge, IDIBELL (Institut D’investigació Biomèdica de Bellvitge), Universitat de Barcelona, Barcelona, Spain
⨯
Josefina Ayats,

Affiliation Hospital Universitari de Bellvitge, IDIBELL (Institut D’investigació Biomèdica de Bellvitge), Universitat de Barcelona, Barcelona, Spain
⨯
Jordi Carratalà

Affiliation Hospital Universitari de Bellvitge, IDIBELL (Institut D’investigació Biomèdica de Bellvitge), Universitat de Barcelona, Barcelona, Spain
⨯

Effect of Statin Use on Outcomes of Adults with Candidemia

Guillermo Cuervo,
Carolina Garcia-Vidal,
Marcio Nucci,
Francesc Puchades,
Mario Fernández-Ruiz,
Analía Mykietiuk,
Adriana Manzur,
Carlota Gudiol,
Javier Pemán,
Diego Viasus

Published: October 14, 2013
https://doi.org/10.1371/journal.pone.0077317

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Statins preventing candida colonization or infection

Posted by tkourkou on 19 Oct 2013 at 23:26 GMT

This is certainly an extremely validating study for the use of statins against Candida infection. One needs to note that statins have been also shown to be effective in the prevention of Candida colonization in the first clinical study of the field here:

Spanakis, Elias K., et al. "Statin Therapy and Decreased Incidence of Positive< i> Candida</i> Cultures Among Patients With Type 2 Diabetes Mellitus Undergoing Gastrointestinal Surgery." Mayo Clinic Proceedings. Vol. 85. No. 12. Elsevier, 2010.

No competing interests declared.

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Effect of Statin Use on Outcomes of Adults with Candidemia

Effect of Statin Use on Outcomes of Adults with Candidemia

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Statins preventing candida colonization or infection

Posted by tkourkou on 19 Oct 2013 at 23:26 GMT