Intranasal Application of S. epidermidis Prevents Colonization by Methicillin-Resistant Staphylococcus aureus in Mice

Bonggoo Park; Tadayuki Iwase; George Y. Liu

doi:10.1371/journal.pone.0025880

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Research Article

Intranasal Application of S. epidermidis Prevents Colonization by Methicillin-Resistant Staphylococcus aureus in Mice

Bonggoo Park,

Affiliation Division of Infectious Diseases, Department of Pediatrics, Research Division of Immunology, Department of Biomedical Sciences, and the Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
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Tadayuki Iwase,

Affiliation Department of Bacteriology, The Jikei University School of Medicine, Tokyo, Japan
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George Y. Liu

* E-mail: george.liu@cshs.org

Affiliation Division of Infectious Diseases, Department of Pediatrics, Research Division of Immunology, Department of Biomedical Sciences, and the Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
⨯

Intranasal Application of S. epidermidis Prevents Colonization by Methicillin-Resistant Staphylococcus aureus in Mice

Bonggoo Park,
Tadayuki Iwase,
George Y. Liu

Published: October 5, 2011
https://doi.org/10.1371/journal.pone.0025880

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Good step towards exploring the use of probiotics in disease prevention

Posted by ramy on 06 Oct 2011 at 18:44 GMT

This is a small, well-performed proof of concept study on using human-associated bacteria to compete with a multiresistant pathogen. It is a first step that I expect to have a big impact on using probiotics more boldly in the future.

Competing interests declared: Although I have never worked with Dr. Liu directly, we co-authored a paper in 2006 (http://www.ncbi.nlm.nih.gov/pubmed/16488874 ) through a common collaborator.

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Intranasal Application of S. epidermidis Prevents Colonization by Methicillin-Resistant Staphylococcus aureus in Mice

Intranasal Application of S. epidermidis Prevents Colonization by Methicillin-Resistant Staphylococcus aureus in Mice

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Good step towards exploring the use of probiotics in disease prevention

Posted by ramy on 06 Oct 2011 at 18:44 GMT