Cochlin Induced TREK-1 Co-Expression and Annexin A2 Secretion: Role in Trabecular Meshwork Cell Elongation and Motility

Manik Goel; Adam E. Sienkiewicz; Renata Picciani; Richard K. Lee; Sanjoy K. Bhattacharya

doi:10.1371/journal.pone.0023070

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Open Access

Peer-reviewed

Research Article

Cochlin Induced TREK-1 Co-Expression and Annexin A2 Secretion: Role in Trabecular Meshwork Cell Elongation and Motility

Manik Goel,

Affiliation Bascom Palmer Eye Institute, University of Miami, Miami, Florida, United States of America
⨯
Adam E. Sienkiewicz,

Affiliation Bascom Palmer Eye Institute, University of Miami, Miami, Florida, United States of America
⨯
Renata Picciani,

Affiliation Bascom Palmer Eye Institute, University of Miami, Miami, Florida, United States of America
⨯
Richard K. Lee,

Affiliation Bascom Palmer Eye Institute, University of Miami, Miami, Florida, United States of America
⨯
Sanjoy K. Bhattacharya

* E-mail: Sbhattacharya@med.miami.edu

Affiliation Bascom Palmer Eye Institute, University of Miami, Miami, Florida, United States of America
⨯

Cochlin Induced TREK-1 Co-Expression and Annexin A2 Secretion: Role in Trabecular Meshwork Cell Elongation and Motility

Manik Goel,
Adam E. Sienkiewicz,
Renata Picciani,
Richard K. Lee,
Sanjoy K. Bhattacharya

Published: August 23, 2011
https://doi.org/10.1371/journal.pone.0023070

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Posted by apatel1 on 29 Aug 2011 at 15:06 GMT

This is a very important study. Not only will it help increase our understanding of the functional changes in the trabecular meshwork during glaucoma, but it may also help identify key regulators of the disease that can be pursed as therapeutic targets.

No competing interests declared.

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Cochlin Induced TREK-1 Co-Expression and Annexin A2 Secretion: Role in Trabecular Meshwork Cell Elongation and Motility

Cochlin Induced TREK-1 Co-Expression and Annexin A2 Secretion: Role in Trabecular Meshwork Cell Elongation and Motility

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Posted by apatel1 on 29 Aug 2011 at 15:06 GMT