Directed Partial Correlation: Inferring Large-Scale Gene Regulatory Network through Induced Topology Disruptions

Yinyin Yuan; Chang-Tsun Li; Oliver Windram

doi:10.1371/journal.pone.0016835

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Open Access

Peer-reviewed

Research Article

Directed Partial Correlation: Inferring Large-Scale Gene Regulatory Network through Induced Topology Disruptions

Yinyin Yuan ,

* E-mail: yy341@cam.ac.uk

Affiliations Cancer Research UK, Cambridge Research Institute, Cambridge, United Kingdom, Department of Oncology, University of Cambridge, Cambridge, United Kingdom
⨯
Chang-Tsun Li,

Affiliation Department of Computer Science, University of Warwick, Coventry, United Kingdom
⨯
Oliver Windram

Affiliation Warwick Horticulture Research Institute, University of Warwick, Wellesbourne, United Kingdom
⨯

Directed Partial Correlation: Inferring Large-Scale Gene Regulatory Network through Induced Topology Disruptions

Yinyin Yuan,
Chang-Tsun Li,
Oliver Windram

Published: April 6, 2011
https://doi.org/10.1371/journal.pone.0016835

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Partial correlation matrix

Posted by Luis_Peraza on 03 Jan 2013 at 13:15 GMT

Indeed the partial correlation matrix has interesting properties. I published a very similar development using this matrix that I called time-lagged partial correlation matrix (here as DPC) and yes, it is an interesting approach for network inference.

[1] A fast dynamic Bayesian network algorithm for structure learning using a time-lagged partial correlation matrix.
http://ieeexplore.ieee.or...

No competing interests declared.

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Directed Partial Correlation: Inferring Large-Scale Gene Regulatory Network through Induced Topology Disruptions

Directed Partial Correlation: Inferring Large-Scale Gene Regulatory Network through Induced Topology Disruptions

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Partial correlation matrix

Posted by Luis_Peraza on 03 Jan 2013 at 13:15 GMT