Nucleotide Sequence Variation within the PI3K p85 Alpha Gene Associates with Alcohol Risk Drinking Behaviour in Adolescents

Sylvane Desrivières; Kristina Krause; Anne Dyer; Josef Frank; Dorothea Blomeyer; Mark Lathrop; Karl Mann; Tobias Banaschewski; Manfred Laucht; Gunter Schumann

doi:10.1371/journal.pone.0001769

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Peer-reviewed

Research Article

Nucleotide Sequence Variation within the PI3K p85 Alpha Gene Associates with Alcohol Risk Drinking Behaviour in Adolescents

Sylvane Desrivières ,

Contributed equally to this work with: Sylvane Desrivières, Kristina Krause

Affiliation Section of Addiction Biology, Interdisciplinary Research Group “Addiction” and NIHR-Biomedical Research Centre, Institute of Psychiatry, King's College, London, United Kingdom
⨯
Kristina Krause ,

Contributed equally to this work with: Sylvane Desrivières, Kristina Krause

Affiliations Section of Addiction Biology, Interdisciplinary Research Group “Addiction” and NIHR-Biomedical Research Centre, Institute of Psychiatry, King's College, London, United Kingdom, Molecular Genetics Laboratory, Department of Addiction Medicine, Central Institute of Mental Health, Mannheim, Germany
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Anne Dyer,

Affiliation Department of Psychosomatic Medicine, Central Institute of Mental Health, Mannheim, Germany
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Josef Frank,

Affiliation Molecular Genetics Laboratory, Department of Addiction Medicine, Central Institute of Mental Health, Mannheim, Germany
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Dorothea Blomeyer,

Affiliation Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
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Mark Lathrop,

Affiliation Centre National de Genotypage, Evry, Paris
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Karl Mann,

Affiliation Molecular Genetics Laboratory, Department of Addiction Medicine, Central Institute of Mental Health, Mannheim, Germany
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Tobias Banaschewski,

Affiliation Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany
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Manfred Laucht ,

* E-mail: manfred.laucht@zi-mannheim.de

Affiliations Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany, Division of Clinical Psychology, Department of Psychology, University of Potsdam, Germany
⨯
Gunter Schumann

Affiliations Section of Addiction Biology, Interdisciplinary Research Group “Addiction” and NIHR-Biomedical Research Centre, Institute of Psychiatry, King's College, London, United Kingdom, Molecular Genetics Laboratory, Department of Addiction Medicine, Central Institute of Mental Health, Mannheim, Germany
⨯

Nucleotide Sequence Variation within the PI3K p85 Alpha Gene Associates with Alcohol Risk Drinking Behaviour in Adolescents

Sylvane Desrivières,
Kristina Krause,
Anne Dyer,
Josef Frank,
Dorothea Blomeyer,
Mark Lathrop,
Karl Mann,
Tobias Banaschewski,
Manfred Laucht,
Gunter Schumann

Published: March 12, 2008
https://doi.org/10.1371/journal.pone.0001769

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Academic Editor's comments (Andreas Heinz)

Posted by PLOS_ONE_Group on 18 Mar 2008 at 09:56 GMT

This is a very interesting, novel finding. The authors followed all suggested changes and answered all queries, the paper now deserves publication

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N.B. These are the comments made by the referee when reviewing an earlier version of this paper. Prior to publication the manuscript has been revised in light of these comments and to address other editorial requirements.

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Single nucleotide polymorphisms
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Nucleotide Sequence Variation within the PI3K p85 Alpha Gene Associates with Alcohol Risk Drinking Behaviour in Adolescents

Nucleotide Sequence Variation within the PI3K p85 Alpha Gene Associates with Alcohol Risk Drinking Behaviour in Adolescents

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Academic Editor's comments (Andreas Heinz)

Posted by PLOS_ONE_Group on 18 Mar 2008 at 09:56 GMT