Lowe Syndrome Protein OCRL1 Supports Maturation of Polarized Epithelial Cells

Open Access

Peer-reviewed

Research Article

Adam G. Grieve ,

Contributed equally to this work with: Adam G. Grieve, Rachel D. Daniels

Current address: Hubrecht Institute for Stem Cell Research and Developmental Biology, Utrecht, The Netherlands

Affiliation Department of Cell Biology, UCL Institute of Ophthalmology, London, United Kingdom
⨯
Rachel D. Daniels ,

Contributed equally to this work with: Adam G. Grieve, Rachel D. Daniels

Affiliation Department of Cell Biology, UCL Institute of Ophthalmology, London, United Kingdom
⨯
Elena Sanchez-Heras,

Affiliation Department of Cell Biology, UCL Institute of Ophthalmology, London, United Kingdom
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Matthew J. Hayes,

Affiliation Department of Cell Biology, UCL Institute of Ophthalmology, London, United Kingdom
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Stephen E. Moss,

Affiliation Department of Cell Biology, UCL Institute of Ophthalmology, London, United Kingdom
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Karl Matter,

Affiliation Department of Cell Biology, UCL Institute of Ophthalmology, London, United Kingdom
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Martin Lowe,

Affiliation Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
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Timothy P. Levine

* E-mail: tim.levine@ucl.ac.uk

Affiliation Department of Cell Biology, UCL Institute of Ophthalmology, London, United Kingdom
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Reader Comments

(A, D, E & F
http://plosone.org/article/info:doi/10.1371/journal.pone.0024044#pone-0024044-g003

No experiments are presented on Inpp5b. They were in part (F) of this figure that was removed in the resubmitted version of the paper.

No competing interests declared.

Epithelial cells
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Immunoprecipitation
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Tight junctions
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Cell staining
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Small interfering RNA
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Caco-2 cells
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Junctional complexes
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Actins
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