Cancer Risk in Children and Adolescents with Birth Defects: A Population-Based Cohort Study

Lorenzo D. Botto; Timothy Flood; Julian Little; Mark N. Fluchel; Sergey Krikov; Marcia L. Feldkamp; Yuan Wu; Rhinda Goedken; Soman Puzhankara; Paul A. Romitti

doi:10.1371/journal.pone.0069077

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Open Access

Peer-reviewed

Research Article

Cancer Risk in Children and Adolescents with Birth Defects: A Population-Based Cohort Study

Lorenzo D. Botto ,

* E-mail: Lorenzo.botto@hsc.utah.edu

Affiliation Division of Medical Genetics, Department of Pediatrics, University of Utah, Salt Lake City, Utah, United States of America
⨯
Timothy Flood,

Affiliation Arizona Department of Health Services, Phoenix, Arizona, United States of America
⨯
Julian Little,

Affiliation Department of Epidemiology and Community Medicine, University of Ottawa, Ontario, Canada
⨯
Mark N. Fluchel,

Affiliation Division of Pediatric Hematology and Oncology, Department of Pediatrics, University of Utah, Salt Lake City, Utah, United States of America
⨯
Sergey Krikov,

Affiliation Division of Medical Genetics, Department of Pediatrics, University of Utah, Salt Lake City, Utah, United States of America
⨯
Marcia L. Feldkamp,

Affiliation Division of Medical Genetics, Department of Pediatrics, University of Utah, Salt Lake City, Utah, United States of America
⨯
Yuan Wu,

Affiliation Department of Epidemiology, College of Public Health, The University of Iowa, Iowa City, Iowa, United States of America
⨯
Rhinda Goedken,

Affiliation Department of Epidemiology, College of Public Health, The University of Iowa, Iowa City, Iowa, United States of America
⨯
Soman Puzhankara,

Affiliation Department of Epidemiology, College of Public Health, The University of Iowa, Iowa City, Iowa, United States of America
⨯
Paul A. Romitti

Affiliation Department of Epidemiology, College of Public Health, The University of Iowa, Iowa City, Iowa, United States of America
⨯

Cancer Risk in Children and Adolescents with Birth Defects: A Population-Based Cohort Study

Lorenzo D. Botto,
Timothy Flood,
Julian Little,
Mark N. Fluchel,
Sergey Krikov,
Marcia L. Feldkamp,
Yuan Wu,
Rhinda Goedken,
Soman Puzhankara,
Paul A. Romitti

Published: July 17, 2013
https://doi.org/10.1371/journal.pone.0069077

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Leukemia (ALL) in Congenital Hydrocephalus

Posted by dlspike on 06 Sep 2015 at 02:13 GMT

Please provide a primary contact for this study to discuss a current incident for a child diagnosed with hydrocephalus (non-tumor related) before birth in 2011. Same child was then later diagnosed with leukemia (ALL) one week prior to her 4th birthday in January 2015. Leukemia diagnosis followed multiple Urgent Care and/or ER visits for various infections, fever and seizure episodes.

No competing interests declared.

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Birth defects
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Children
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Cancer Risk in Children and Adolescents with Birth Defects: A Population-Based Cohort Study

Cancer Risk in Children and Adolescents with Birth Defects: A Population-Based Cohort Study

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Leukemia (ALL) in Congenital Hydrocephalus

Posted by dlspike on 06 Sep 2015 at 02:13 GMT