An Assessment of the Screening Method to Evaluate Vaccine Effectiveness: The Case of 7-Valent Pneumococcal Conjugate Vaccine in the United States

Adam L. Cohen; Thomas Taylor Jr; Monica M. Farley; William Schaffner; Lindsey J. Lesher; Kenneth A. Gershman; Nancy M. Bennett; Arthur Reingold; Ann Thomas; Joan Baumbach; Lee H. Harrison; Susan Petit; Bernard Beall; Elizabeth Zell; Matthew Moore

doi:10.1371/journal.pone.0041785

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Open Access

Peer-reviewed

Research Article

An Assessment of the Screening Method to Evaluate Vaccine Effectiveness: The Case of 7-Valent Pneumococcal Conjugate Vaccine in the United States

Adam L. Cohen ,

* E-mail: dvj1@cdc.gov

Affiliation Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Thomas Taylor Jr,

Affiliation Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Monica M. Farley,

Affiliation Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
William Schaffner,

Affiliation Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
Lindsey J. Lesher,

Affiliation Minnesota Department of Health, St. Paul, Minnesota, United States of America
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Kenneth A. Gershman,

Affiliation Colorado Department of Health and the Environment, Denver, Colorado, United States of America
⨯
Nancy M. Bennett,

Affiliation Rochester University School of Medicine, Rochester, New York, United States of America
⨯
Arthur Reingold,

Affiliation University of California, Berkeley, California, United States of America
⨯
Ann Thomas,

Affiliation Oregon Department of Health, Portland, Oregon, United States of America
⨯
Joan Baumbach,

Affiliation New Mexico Department of Health, Santa Fe, New Mexico, United States of America
⨯
Lee H. Harrison,

Affiliation Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America
⨯
Susan Petit,

Affiliation Connecticut Department of Public Health, Hartford, Connecticut, United States of America
⨯
Bernard Beall,

Affiliation Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Elizabeth Zell,

Affiliation Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Matthew Moore

Affiliation Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯

An Assessment of the Screening Method to Evaluate Vaccine Effectiveness: The Case of 7-Valent Pneumococcal Conjugate Vaccine in the United States

Adam L. Cohen,
Thomas Taylor Jr,
Monica M. Farley,
William Schaffner,
Lindsey J. Lesher,
Kenneth A. Gershman,
Nancy M. Bennett,
Arthur Reingold,
Ann Thomas,
Joan Baumbach

Published: August 1, 2012
https://doi.org/10.1371/journal.pone.0041785

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Vaccine effctiveness calculation

Posted by pmarkey on 30 Jan 2017 at 07:52 GMT

Apologies if it has already been corrected but shouldn't the last line of the formula for VE in the methods have a "1-" in front of it. As it stands if the coverage rate and proportion of cases vaccinated were the same then VE would equal 100%.

No competing interests declared.

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An Assessment of the Screening Method to Evaluate Vaccine Effectiveness: The Case of 7-Valent Pneumococcal Conjugate Vaccine in the United States

An Assessment of the Screening Method to Evaluate Vaccine Effectiveness: The Case of 7-Valent Pneumococcal Conjugate Vaccine in the United States

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Vaccine effctiveness calculation

Posted by pmarkey on 30 Jan 2017 at 07:52 GMT