Adaptive Pacing, Cognitive Behaviour Therapy, Graded Exercise, and Specialist Medical Care for Chronic Fatigue Syndrome: A Cost-Effectiveness Analysis

Paul McCrone; Michael Sharpe; Trudie Chalder; Martin Knapp; Anthony L. Johnson; Kimberley A. Goldsmith; Peter D. White

doi:10.1371/journal.pone.0040808

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Open Access

Peer-reviewed

Research Article

Adaptive Pacing, Cognitive Behaviour Therapy, Graded Exercise, and Specialist Medical Care for Chronic Fatigue Syndrome: A Cost-Effectiveness Analysis

Paul McCrone ,

* E-mail: paul.mccrone@kcl.ac.uk

Affiliation Centre for the Economics of Mental and Physical Health, Health Service and Population Research Department, Institute of Psychiatry, King’s College London, London, United Kingdom
⨯
Michael Sharpe,

Affiliation University Department of Psychiatry, University of Oxford, Oxford, United Kingdom
⨯
Trudie Chalder,

Affiliation Academic Department of Psychological Medicine, King’s College London, London, United Kingdom
⨯
Martin Knapp,

Affiliations Centre for the Economics of Mental and Physical Health, Health Service and Population Research Department, Institute of Psychiatry, King’s College London, London, United Kingdom, Personal Social Services Research Unit, London School of Economics, London, United Kingdom
⨯
Anthony L. Johnson,

Affiliations MRC Biostatistics Unit, Institute of Public Health, Cambridge, United Kingdom, MRC Clinical Trials Unit, London, United Kingdom
⨯
Kimberley A. Goldsmith,

Affiliation Biostatistics Department, Institute of Psychiatry, King’s College London, London, United Kingdom
⨯
Peter D. White

Affiliation Centre for Psychiatry, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
⨯

Adaptive Pacing, Cognitive Behaviour Therapy, Graded Exercise, and Specialist Medical Care for Chronic Fatigue Syndrome: A Cost-Effectiveness Analysis

Paul McCrone,
Michael Sharpe,
Trudie Chalder,
Martin Knapp,
Anthony L. Johnson,
Kimberley A. Goldsmith,
Peter D. White

Published: August 1, 2012
https://doi.org/10.1371/journal.pone.0040808

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Media Coverage of This Article

Posted by PLOS_ONE_Group on 06 Aug 2012 at 20:14 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: ActiveQuote
Title: “CBT and GET are cost effective treatments for chro.. | News | ActiveQuote”
http://www.activequote.co...

Publication: BBC News
Title: “BBC News - Chronic fatigue syndrome: Brain training is most cost-effective treatment”
http://www.bbc.co.uk/news...

Publication: Health Canal
Title: “Health News - Two effective treatments for CFS/ME are also cost-effective”
http://www.healthcanal.co...

Publication: Healthcare Today
Title: “New help for ME sufferers | News | Healthcare Today UK”
http://www.healthcare-tod...

Publication: Joy Online
Title: “Chronic fatigue syndrome: Brain training is most cost-effective treatment | Health”
http://lifestyle.myjoyonl...

Publication: King's College London
Title: “Two effective treatments for CFS/ME also cost-effective”
http://www.kcl.ac.uk/iop/...

Publication: Medical Research Council
Title: “Medical Research Council | News | Two effective treatments for CFS/ME are also cost-effective”
http://www.mrc.ac.uk/News...

Publication: NetDoctor.co.uk
Title: “Health News - Two treatments for CFS/ME 'are cost-effective'”
http://www.netdoctor.co.u...

Publication: NHS Choices
Title: “Pacing for chronic fatigue syndrome 'not cost-effective' - Health News - NHS Choices”
http://www.nhs.uk/news/20...

Publication: The British Psychological Society
Title: “Behavioural therapies can help with ME | BPS”
http://www.bps.org.uk/new...

Publication: The Independent
Title: “Two chronic fatigue syndrome treatments offer good value - Health News - Health & Families - The Independent”
http://www.independent.co...

Publication: The Information Daily
Title: “New recommendations for treating fatigue could save economy millions | eGov monitor | The Information Daily”
http://www.egovmonitor.co...

Publication: TopNews Arab Emirates
Title: “2 Cost Effective Ways to Treat CFS | TopNews Arab Emirates”
http://topnews.ae/content...

Publication: UKPA
Title: “The Press Association: Two CFS treatments offer good value”
http://www.google.com/hos...

Publication: WebMD
Title: “CBT 'most effective' for chronic fatigue syndrome (CFS/ME)”
http://www.webmd.boots.co...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLOS ONE Staff

RE: Media Coverage of This Article

AngelaKennedy replied to PLOS_ONE_Group on 07 Aug 2012 at 06:02 GMT

The articles above demonstrate how easily the results of medical studies are misrepresented and exaggerated in all sections of public, medical and academic press and media. As a result of such misrepresentation of this paper (and the PACE study's first Lancet paper), and the unsafe claims to efficacy, from both papers themselves, but then further exaggerated by articles such as those cited above, patients will be put at further risk as they are exhorted to try, what remain dangerous treatments, by doctors, the DWP, and the community at large.

Authors of such studies have an ethical duty to patients, to prevent placing them in danger by taking particular care not to misrepresent or exaggerate their findings or claims when disseminating their studies to the press.

Competing interests declared: Social scientist with interest in research methodology; author of forthcoming book critiquing psychogenic explanations of physical illnesses; parent and carer of woman with chronic illness and disability who became ill as a child.