Inhibitors of Helicobacter pylori Protease HtrA Found by ‘Virtual Ligand’ Screening Combat Bacterial Invasion of Epithelia

• Martin Löwer ,

  Contributed equally to this work with: Martin Löwer, Tim Geppert

  Affiliation Institute of Organic Chemistry and Chemical Biology, Goethe-University, Frankfurt, Germany

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• Tim Geppert ,

  Contributed equally to this work with: Martin Löwer, Tim Geppert

  Affiliation Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology (ETH), Zürich, Switzerland

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• Petra Schneider,

  Affiliation Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology (ETH), Zürich, Switzerland

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• Benjamin Hoy,

  Affiliation Division of Microbiology, University of Salzburg, Salzburg, Austria

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• Silja Wessler ,

  ¶These authors also contributed equally to this work.

  Affiliation Division of Microbiology, University of Salzburg, Salzburg, Austria

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• Gisbert Schneider

  * E-mail: gisbert.schneider@pharma.ethz.ch

  ¶These authors also contributed equally to this work.

  Affiliation Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology (ETH), Zürich, Switzerland

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