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Enlightening paper

Posted by dawe on 11 Aug 2009 at 15:33 GMT

I've found this paper enlightening, as it gives a wide, though not complete, benchmark for different sequence map algorithms. As we are dealing with a number of expression profiling experiments, this paper will be surely helpful in choosing alternatives to ELAND.
Besides, it would be interesting to compare ELAND itself with the algorithms discussed here. I suspect that the well known "2 mismatch limit", in addition to the lack of gapped alignment capabilities, may make it perform not better than the worst cases discussed.

No competing interests declared.