Genome-Wide Sequencing of Cellular microRNAs Identifies a Combinatorial Expression Signature Diagnostic of Sepsis

Yuqian Ma; David Vilanova; Kerem Atalar; Olivier Delfour; Jonathan Edgeworth; Marlies Ostermann; Maria Hernandez-Fuentes; Sandrine Razafimahatratra; Bernard Michot; David H. Persing; Ingrid Ziegler; Bianca Törös; Paula Mölling; Per Olcén; Richard Beale; Graham M. Lord

doi:10.1371/journal.pone.0075918

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Research Article

Genome-Wide Sequencing of Cellular microRNAs Identifies a Combinatorial Expression Signature Diagnostic of Sepsis

Yuqian Ma,

Current address: Department of Haematological Medicine, King's College London, London, United Kingdom

Affiliations Department of Experimental Immunobiology, King's College London, London, United Kingdom, NIHR Biomedical Research Centre, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom
⨯
David Vilanova,

Affiliation R&D, Cepheid Europe, Maurens Scopont, France
⨯
Kerem Atalar,

Affiliations Department of Experimental Immunobiology, King's College London, London, United Kingdom, NIHR Biomedical Research Centre, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom
⨯
Olivier Delfour,

Affiliation R&D, Cepheid Europe, Maurens Scopont, France
⨯
Jonathan Edgeworth,

Affiliations NIHR Biomedical Research Centre, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom, Guy's and St Thomas NHS Foundation Trust, London, United Kingdom
⨯
Marlies Ostermann,

Affiliations NIHR Biomedical Research Centre, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom, Guy's and St Thomas NHS Foundation Trust, London, United Kingdom
⨯
Maria Hernandez-Fuentes,

Affiliations Department of Experimental Immunobiology, King's College London, London, United Kingdom, NIHR Biomedical Research Centre, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom
⨯
Sandrine Razafimahatratra,

Affiliation R&D, Cepheid Europe, Maurens Scopont, France
⨯
Bernard Michot,

Affiliation R&D, Cepheid Europe, Maurens Scopont, France
⨯
David H. Persing,

Affiliation Cepheid, Sunnyvale, California, United States of America
⨯
Ingrid Ziegler,

Affiliation Department of Infectious Diseases, Örebro University Hospital, Örebro, Sweden
⨯
Bianca Törös,

Affiliation Department of Laboratory Medicine, Clinical Microbiology, Örebro University Hospital, Örebro, Sweden
⨯
Paula Mölling,

Affiliation Department of Laboratory Medicine, Clinical Microbiology, Örebro University Hospital, Örebro, Sweden
⨯
Per Olcén,

Affiliation Department of Laboratory Medicine, Clinical Microbiology, Örebro University Hospital, Örebro, Sweden
⨯
Richard Beale,

Affiliations Division of Asthma, Allergy and Lung Biology, King's College London, London, United Kingdom, NIHR Biomedical Research Centre, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom, Guy's and St Thomas NHS Foundation Trust, London, United Kingdom
⨯
[ ... ],
Graham M. Lord

* E-mail: graham.lord@kcl.ac.uk

Affiliations Department of Experimental Immunobiology, King's College London, London, United Kingdom, NIHR Biomedical Research Centre, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom, Guy's and St Thomas NHS Foundation Trust, London, United Kingdom
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Genome-Wide Sequencing of Cellular microRNAs Identifies a Combinatorial Expression Signature Diagnostic of Sepsis

Yuqian Ma,
David Vilanova,
Kerem Atalar,
Olivier Delfour,
Jonathan Edgeworth,
Marlies Ostermann,
Maria Hernandez-Fuentes,
Sandrine Razafimahatratra,
Bernard Michot,
David H. Persing

Published: October 16, 2013
https://doi.org/10.1371/journal.pone.0075918

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Posted by PLOS_ONE_Group on 25 Oct 2013 at 23:03 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: SBS
Title: “New blood test could help thousands | SBS News”
http://www.sbs.com.au/new...

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Competing interests declared: PLOS ONE staff

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Genome-Wide Sequencing of Cellular microRNAs Identifies a Combinatorial Expression Signature Diagnostic of Sepsis

Genome-Wide Sequencing of Cellular microRNAs Identifies a Combinatorial Expression Signature Diagnostic of Sepsis

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Media coverage for this article

Posted by PLOS_ONE_Group on 25 Oct 2013 at 23:03 GMT