Volume of hyperintense inflammation (V_HI): A quantitative imaging biomarker of inflammation load in spondyloarthritis, enabled by human-machine cooperation

• Carolyna Hepburn,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Visualization, Writing – original draft

  Affiliations Centre for Medical Imaging, University College London, London, United Kingdom, Centre for Medical Image Computing, University College London, London, United Kingdom

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• Alexis Jones,

  Roles Conceptualization, Data curation, Project administration, Writing – original draft

  Affiliations Centre for Medical Imaging, University College London, London, United Kingdom, Centre for Adolescent Rheumatology, University College London, London, United Kingdom

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• Alan Bainbridge,

  Roles Conceptualization, Data curation, Investigation, Resources, Writing – original draft

  Affiliation Department of Medical Physics, University College London Hospitals, London, United Kingdom

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• Coziana Ciurtin,

  Roles Investigation, Resources, Writing – original draft

  Affiliation Centre for Adolescent Rheumatology, University College London, London, United Kingdom

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• Juan Eugenio Iglesias,

  Roles Methodology, Project administration, Software, Supervision

  Affiliations Centre for Medical Image Computing, University College London, London, United Kingdom, Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Boston, Massachusetts, United States of America, Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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• Hui Zhang ,

  Roles Conceptualization, Investigation, Project administration, Resources, Writing – review & editing

  ¶‡ HZ, MAHC and TJPB are joint senior authorship on this work.

  Affiliation Centre for Medical Image Computing, University College London, London, United Kingdom

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• Margaret A. Hall-Craggs ,

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  ¶‡ HZ, MAHC and TJPB are joint senior authorship on this work.

  Affiliations Centre for Medical Imaging, University College London, London, United Kingdom, Imaging Department, University College London Hospital, London, United Kingdom

  https://orcid.org/0000-0001-8734-4065

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• Timothy J. P. Bray

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: t.bray@ucl.ac.uk

  ¶‡ HZ, MAHC and TJPB are joint senior authorship on this work.

  Affiliations Centre for Medical Imaging, University College London, London, United Kingdom, Imaging Department, University College London Hospital, London, United Kingdom

  https://orcid.org/0000-0001-8886-5356

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